KFO309 - The clinical research unit Virus Induced Lung injury

All Publications

SARS-CoV-2 entry factors are highly expressed in nasal epithelial cells together with innate immune genes

Sungnak W, Huang N, Bécavin C, Berg M, Queen R, Litvinukova M, Talavera-López C, Maatz H, Reichart D, Sampaziotis F, Worlock KB, Yoshida M, Barnes JL & HCA Lung Biological Network

Nature Medicine 2020 May;26(5):681-687. doi: 10.1038/s41591-020-0868-6

The endocannabinoid anandamide has an anti-inflammatory effect on CCL2 expression in vascular smooth muscle cells

Pflüger-Müller B, Oo JA, Heering J, Warwick T, Proschak E, Günther S, Looso M, Rezende F, Fork C, Geisslinger G, Thomas D, Gurke R, Steinhilber D, Schulz M, Leisegang MS, Brandes RP

Basic Res Cardiol 2020 Apr 22;115(3):34. doi: 10.1007/s00395-020-0793-3

Noncoding RNA MaIL1 is an integral component of the TLR4-TRIF pathway

Aznaourova M, Janga H, Sefried S, Kaufmann A, Dorna J, Volkers SM, Georg P, Lechner M, Hoppe J, Dökel S, Schmerer N, Gruber AD, Linne U, Bauer S, Sander LE, Schmeck B, Schulte LN

Proc Natl Acad Sci U S A 2020 Apr 21;117(16):9042-9053. doi: 10.1073/pnas.1920393117

Evidence for Overlapping and Distinct Biological Activities and Transcriptional Targets Triggered by Fibroblast Growth Factor Receptor 2b Signaling between Mid- and Early Pseudoglandular Stages of Mouse Lung Development

Jones M, Lingampally A, Wu J, Sedighi J, Ahmadvand N, Wilhelm J, Vazquez-Armendariz I, Herold S, Chen C, Zhang JS, Bellusci S, Chao CM

Cells 2020 9:1274

HDAC3 functions as a positive regulator in Notch signal transduction

Ferrante F, Giaimo BD, Bartkuhn M, Zimmermann T, Close V, Mertens D, Nist A, Stiewe T, Meier-Soelch J, Kracht M, Just S, Klöble P, Oswald F, Borggrefe T

Nucleic Acids Res 2020 Apr 17;48(7):3496-3512. doi: 10.1093/nar/gkaa088

The Integrity of the YxxL Motif of Ebola Virus VP24 Is Important for the Transport of Nucleocapsid-Like Structures and for the Regulation of Viral RNA Synthesis

Takamatsu Y, Kolesnikova L, Schauflinger M, Noda T, Becker S

J Virol 2020 Apr 16;94(9):e02170-19. doi: 10.1128/JVI.02170-19

Bypassing mitochondrial complex III using alternative oxidase inhibits acute pulmonary oxygen sensing

Sommer N, Alebrahimdehkordi N, Pak O, Knoepp F, Strielkov I, Scheibe S, Dufour E, Andjelković A, Sydykov A, Saraji A, Petrovic A, Quanz K, Hecker M, Kumar M, Wahl J, Kraut S, Seeger W, Schermuly RT, Ghofrani HA, Ramser K, Braun T, Jacobs HT, Weissmann N, Szibor M

Sci Adv 2020 Apr 15;6(16):eaba0694. doi: 10.1126/sciadv.aba0694

Signal regulators of human naïve pluripotency

Taei A, Rasooli P, Braun T, Hassani SN, Baharvand H

Exp Cell Res 2020 Apr 15;389(2):111924. doi: 10.1016/j.yexcr.2020.111924

Chemosensory Cell-Derived Acetylcholine Drives Tracheal Mucociliary Clearance in Response to Virulence-Associated Formyl Peptides

Perniss A, Liu S, Boonen B, Keshavarz M, Ruppert AL, Timm T, Pfeil U, Soultanova A, Kusumakshi S, Delventhal L, Aydin Ö, Pyrski M, Deckmann K, Hain T, Schmidt N, Ewers C, Günther A, Lochnit G, Chubanov V, Gudermann T, Oberwinkler J, Klein J, Mikoshiba K, Leinders-Zufall T, Offermanns S, Schütz B, Boehm U, Zufall F, Bufe B, Kummer W

Immunity 2020 Apr 14;52(4):683-699.e11. doi: 10.1016/j.immuni.2020.03.005

Novel Liquid Biomarker Panels for A Very Early Response Capturing of NSCLC Therapies in Advanced Stages

Janke F, Bozorgmehr F, Wrenger S, Dietz S, Heussel CP, Heussel G, Silva CF, Rheinheimer S, Feisst M, Thomas M, Golpon H, Günther A, Sültmann H, Muley T, Janciauskiene S, Meister M, Schneider MA

Cancers (Basel) 2020 Apr 12;12(4):954. doi: 10.3390/cancers12040954

Fibroblast Growth Factors in the Management of Acute Kidney Injury Following Ischemia-Reperfusion

Deng LC, Alinejad T, Bellusci S, Zhang JS

Front Pharmacol 2020 Apr 8;11:426. doi: 10.3389/fphar.2020.00426

The species Severe acute respiratory syndrome-related coronavirus: classifying 2019-nCoV and naming it SARS-CoV-2

Coronaviridae Study Group of the International Committee on Taxonomy of Viruses

Nat Microbiol 2020 Apr;5(4):536-544. doi: 10.1038/s41564-020-0695-z

Failure to Down-Regulate miR-154 Expression in Early Postnatal Mouse Lung Epithelium Suppresses Alveologenesis, with Changes in Tgf-β Signaling Similar to those Induced by Exposure to Hyperoxia

Chao CM, Carraro G, Rako ZA, Kolck J, Sedighi J, Zimmermann V, Moiseenko A, Wilhelm J, Young BM, Chong L, Wu J, Contreras A, Minoo P, Barreto G, Warburton D, Bellusci S

Cells 2020 Apr 2;9(4). pii: E859. doi: 10.3390/cells9040859

Hexamer phasing governs transcription initiation in the 3'-leader of Ebola virus

Bach S, Biedenkopf N, Grünweller A, Becker S, Hartmann RK

RNA 2020 Apr;26(4):439-453. doi: 10.1261/rna.073718.119

PDGFRα and αSMA mark two distinct mesenchymal cell populations involved in parenchymal and vascular remodeling in pulmonary fibrosis

Biasin V, Crnkovic S, Sahu-Osen A, Birnhuber A, El Agha E, Sinn K, Klepetko W, Olschewski A, Bellusci S, Marsh LM, Kwapiszewska G

Am J Physiol Lung Cell Mol Physiol 2020 Apr 1;318(4):L684-L697. doi: 10.1152/ajplung.00128.2019