KFO309 - The clinical research unit Virus Induced Lung injury

All Publications

ATAC-seq footprinting unravels kinetics of transcription factor binding during zygotic genome activation

Bentsen M, Goymann P, Schultheis H, Klee K, Petrova A, Wiegandt R, Fust A, Preussner J, Kuenne C, Braun T, Kim J, Looso M

Nat Commun 2020 Aug 26;11(1):4267. doi: 10.1038/s41467-020-18035-1

Safety and Parental Satisfaction With Early Discharge of Preterm Infants on Nasogastric Tube Feeding and Outpatient Clinic Follow-Up

Schuler R, Ehrhardt H, Mihatsch WA

Front Pediatr 2020 Aug 25;8:505. doi: 10.3389/fped.2020.00505

IL-13 as Target to Reduce Cholestasis and Dysbiosis in Abcb4 Knockout Mice

Hahn L, Helmrich N, Herebian D, Mayatepek E, Drebber U, Domann E, Olejniczak S, Weigel M, Hain T, Rath T, Wirtz S, Mollenkopf HJ, Schmidt N, Ewers C, Baier A, Churin Y, Windhorst A, Weiskirchen R, Steinhoff U, Roeb E, Roderfeld M

Cells 2020 Aug 24;9(9):1949. doi: 10.3390/cells9091949

Decreased Thymic Output Contributes to Immune Defects in Septic Patients

Sommer N, Noack S, Hecker A, Hackstein H, Bein G, Weissmann N, Seeger W, Mayer K, Hecker M

J Clin Med 2020 Aug 20;9(9):2695. doi: 10.3390/jcm9092695

Myocyte-Specific Upregulation of ACE2 in Cardiovascular Disease: Implications for SARS-CoV-2-Mediated Myocarditis

Tucker NR, Chaffin M, Bedi KC Jr, Papangeli I, Akkad AD, Arduini A, Hayat S, Eraslan G, Muus C, Bhattacharyya RP, Stegmann CM; Human Cell Atlas Lung Biological Network; Margulies KB, Ellinor PT; Human Cell Atlas Lung Biological Network Consortium Members

Circulation 2020 Aug 18;142(7):708-710. doi: 10.1161/CIRCULATIONAHA.120.047911

Safety and immunogenicity of the ChAdOx1 nCoV-19 vaccine against SARS-CoV-2: a preliminary report of a phase 1/2, single-blind, randomised controlled trial

Folegatti PM, Ewer KJ, Aley PK, Angus B, Becker S, Belij-Rammerstorfer S, Bellamy D, Bibi S, Bittaye M, Clutterbuck EA, Dold C, Faust SN, Finn A, Flaxman AL, Hallis B, Heath P, Jenkin D, Lazarus R, Makinson R, Minassian AM, Pollock KM, Ramasamy M, Robinson H, Snape M, Tarrant R, Voysey M, Green C, Douglas AD, Hill AVS, Lambe T, Gilbert SC, Pollard AJ; Oxford COVID Vaccine Trial Group

Lancet 2020 Aug 15;396(10249):467-478. doi: 10.1016/S0140-6736(20)31604-4

Transcriptome profiling and protease inhibition experiments identify proteases that activate H3N2 influenza A and influenza B viruses in murine airways

Harbig A, Mernberger M, Bittel L, Pleschka S, Schughart K, Steinmetzer T, Stiewe T, Nist A, Böttcher-Friebertshäuser E

J Biol Chem 2020 Aug 14;295(33):11388-11407. doi: 10.1074/jbc.RA120.012635

Targeting Bronchopulmonary Dysplasia-Associated Pulmonary Hypertension (BPD-PH): Potential Role of the FGF Signaling Pathway in the Development of the Pulmonary Vascular System

Chao CM, Chong L, Chu X, Shrestha A, Behnke J, Ehrhardt H, Zhang J, Chen C, Bellusci S

Cells 2020 Aug 11;9(8):1875. doi: 10.3390/cells9081875

Effects of Liberal vs Restrictive Transfusion Thresholds on Survival and Neurocognitive Outcomes in Extremely Low-Birth-Weight Infants: The ETTNO Randomized Clinical Trial

Franz AR, Engel C, Bassler D, Rüdiger M, Thome UH, Maier RF, Krägeloh-Mann I, Kron M, Essers J, Bührer C, Rellensmann G, Rossi R, Bittrich HJ, Roll C, Höhn T, Ehrhardt H, Avenarius S, Körner HT, Stein A, Buxmann H, Vochem M, Poets CF; ETTNO Investigators

JAMA 2020 Aug 11;324(6):560-570. doi: 10.1001/jama.2020.10690

Adjuvant formulated virus-like particles expressing native-like forms of the Lassa virus envelope surface glycoprotein are immunogenic and induce antibodies with broadly neutralizing activity

Müller H, Fehling SK, Dorna J, Urbanowicz RA, Oestereich L, Krebs Y, Kolesnikova L, Schauflinger M, Krähling V, Magassouba N, Fichet-Calvet E, Ball JK, Kaufmann A, Bauer S, Becker S, von Messling V, Strecker T

NPJ Vaccines 2020 Aug 4;5(1):71. doi: 10.1038/s41541-020-00219-x

Clinical and Functional Characteristics of Patients with Unclassifiable Interstitial Lung Disease (uILD): Long-Term Follow-Up Data from European IPF Registry (eurIPFreg)

Krauss E, El-Guelai M, Pons-Kuehnemann J, Dartsch RC, Tello S, Korfei M, Mahavadi P, Breithecker A, Fink L, Stoehr M, Majeed RW, Seeger W, Crestani B, Guenther A

J Clin Med 2020 Aug 3;9(8):2499. doi: 10.3390/jcm9082499

Commercially available transfection reagents and negative control siRNA are not inert

Kleefeldt JM, Pozarska A, Nardiello C, Pfeffer T, Vadász I, Herold S, Seeger W, Morty RE

Anal Biochem 2020 Oct 1;606:113828. doi: 10.1016/j.ab.2020.113828

Besnoitia besnoiti-driven endothelial host cell cycle alteration

Velásquez ZD, Lopez-Osorio S, Pervizaj-Oruqaj L, Herold S, Hermosilla C, Taubert A

Parasitol Res 2020 Aug;119(8):2563-2577. doi: 10.1007/s00436-020-06744-x

Non-invasive risk-assessment and bleeding prophylaxis with IVIG in pregnant women with a history of fetal and neonatal alloimmune thrombocytopenia: management to minimize adverse events

Wienzek-Lischka S, Sawazki A, Ehrhardt H, Sachs UJ, Axt-Fliedner R, Bein G

Arch Gynecol Obstet 2020 Aug;302(2):355-363. doi: 10.1007/s00404-020-05618-y

Correction: The genomic and clinical landscape of fetal akinesia

Pergande M, Motameny S, Özdemir Ö, Kreutzer M, Wang H, Daimagüler HS, Becker K, Karakaya M, Ehrhardt H, Elcioglu N, Ostojic S, Chao CM, Kawalia A, Duman Ö, Koy A, Hahn A, Reimann J, Schoner K, Schänzer A, Westhoff JH, Schwaibold EMC, Cossee M, Imbert-Bouteille M, von Pein H, Haliloglu G, Topaloglu H, Altmüller J, Nürnberg P, Thiele H, Heller R, Cirak S

Genet Med 2020 Aug;22(8):1426-1428. doi: 10.1038/s41436-020-0839-9