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Universitätsklinikum Marburg
Justus-Liebig-Universität Giessen
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KFO309 - The clinical research unit Virus Induced Lung injury

All Publications

Fibroblast growth factor 10 is a negative regulator of postnatal neurogenesis in the mouse hypothalamus

Goodman T, Nayar SG, Clare S, Mikolajczak M, Rice R, Mansour S, Bellusci S, Hajihosseini MK

Development 2020 Jul 13;147(13):dev180950. doi: 10.1242/dev.180950

Acute kidney injury and urinary biomarkers in hospitalized patients with coronavirus disease-2019

Husain-Syed F, Wilhelm J, Kassoumeh S, Birk HW, Herold S, Vadász I, Walmrath HD, Kellum JA, Ronco C, Seeger W

Nephrol Dial Transplant 2020 Jul 1;35(7):1271-1274. doi: 10.1093/ndt/gfaa162

Safety and immunogenicity of a candidate Middle East respiratory syndrome coronavirus viral-vectored vaccine: a dose-escalation, open-label, non-randomised, uncontrolled, phase 1 trial

Folegatti PM, Bittaye M, Flaxman A, Lopez FR, Bellamy D, Kupke A, Mair C, Makinson R, Sheridan J, Rohde C, Halwe S, Jeong Y, Park YS, Kim JO, Song M, Boyd A, Tran N, Silman D, Poulton I, Datoo M, Marshall J, Themistocleous Y, Lawrie A, Roberts R, Berrie E, Becker S, Lambe T, Hill A, Ewer K, Gilbert S

Lancet Infect Dis 2020 Jul;20(7):816-826. doi: 10.1016/S1473-3099(20)30160-2

Safety and immunogenicity of a modified vaccinia virus Ankara vector vaccine candidate for Middle East respiratory syndrome: an open-label, phase 1 trial

Koch T, Dahlke C, Fathi A, Kupke A, Krähling V, Okba NMA, Halwe S, Rohde C, Eickmann M, Volz A, Hesterkamp T, Jambrecina A, Borregaard S, Ly ML, Zinser ME, Bartels E, Poetsch JSH, Neumann R, Fux R, Schmiedel S, Lohse AW, Haagmans BL, Sutter G, Becker S, Addo MM

Lancet Infect Dis 2020 Jul;20(7):827-838. doi: 10.1016/S1473-3099(20)30248-6

Implication of in vivo circulating fibrocytes ablation in experimental pulmonary hypertension murine model

Nikam VS, Nikam S, Sydykov A, Ahlbrecht K, Morty RE, Seeger W, Voswinckel R

Br J Pharmacol 2020 Jul;177(13):2974-2990. doi: 10.1111/bph.15025

Author Correction: NADPH oxidase subunit NOXO1 is a target for emphysema treatment in COPD

Seimetz M, Sommer N, Bednorz M, Pak O, Veith C, Hadzic S, Gredic M, Parajuli N, Kojonazarov B, Kraut S, Wilhelm J, Knoepp F, Henneke I, Pichl A, Kanbagli ZI, Scheibe S, Fysikopoulos A, Wu CY, Klepetko W, Jaksch P, Eichstaedt C, Grünig E, Hinderhofer K, Geiszt M, Müller N, Rezende F, Buchmann G, Wittig I, Hecker M, Hecker A, Padberg W, Dorfmüller P, Gattenlöhner S, Vogelmeier CF, Günther A, Karnati S, Baumgart-Vogt E, Schermuly RT, Ghofrani HA, Seeger W, Schröder K, Grimminger F, Brandes RP, Weissmann N

Nat Metab 2020 Jul;2(7):648. doi: 10.1038/s42255-020-0248-z

RUNX1: an emerging therapeutic target for cardiovascular disease

Riddell A, McBride M, Braun T, Nicklin SA, Cameron E, Loughrey CM, Martin TP

Cardiovasc Res 2020 Jul 1;116(8):1410-1423. doi: 10.1093/cvr/cvaa034

Whole-genome sequencing of patients with rare diseases in a national health system

Turro E, Astle WJ, Megy K, Gräf S, Greene D, Shamardina O, Allen HL, Sanchis-Juan A, Frontini M, Thys C, Stephens J, Mapeta R, Burren OS, Downes K, Haimel M, Tuna S, Deevi SVV, Aitman TJ, Bennett DL, Calleja P, Carss K, Caulfield MJ, Chinnery PF, Dixon PH, Gale DP, James R, Koziell A, Laffan MA, Levine AP, Maher ER, Markus HS, Morales J, Morrell NW, Mumford AD, Ormondroyd E, Rankin S, Rendon A, Richardson S, Roberts I, Roy NBA, Saleem MA, Smith KGC, Stark H, Tan RYY, Themistocleous AC, Thrasher AJ, Watkins H, Webster AR, Wilkins MR, Williamson C, Whitworth J, Humphray S, Bentley DR; NIHR BioResource for the 100,000 Genomes Project; Kingston N, Walker N, Bradley JR, Ashford S, Penkett CJ, Freson K, Stirrups KE, Raymond FL, Ouwehand WH

Nature 2020 Jul;583(7814):96-102. doi: 10.1038/s41586-020-2434-2

Whole-genome sequencing of a sporadic primary immunodeficiency cohort

Thaventhiran JED, Lango Allen H, Burren OS, Rae W, Greene D, Staples E, Zhang Z, Farmery JHR, Simeoni I, Rivers E, Maimaris J, Penkett CJ, Stephens J, Deevi SVV, Sanchis-Juan A, Gleadall NS, Thomas MJ, Sargur RB, Gordins P, Baxendale HE, Brown M, Tuijnenburg P, Worth A, Hanson S, Linger RJ, Buckland MS, Rayner-Matthews PJ, Gilmour KC, Samarghitean C, Seneviratne SL, Sansom DM, Lynch AG, Megy K, Ellinghaus E, Ellinghaus D, Jorgensen SF, Karlsen TH, Stirrups KE, Cutler AJ, Kumararatne DS, Chandra A, Edgar JDM, Herwadkar A, Cooper N, Grigoriadou S, Huissoon AP, Goddard S, Jolles S, Schuetz C, Boschann F; Primary Immunodeficiency Consortium for the NIHR Bioresource; Lyons PA, Hurles ME, Savic S, Burns SO, Kuijpers TW, Turro E, Ouwehand WH, Thrasher AJ, Smith KGC

Nature 2020 Jul;583(7814):90-95. doi: 10.1038/s41586-020-2265-1

Microenvironmental Th9 and Th17 lymphocytes induce metastatic spreading in lung cancer

Salazar Y, Zheng X, Brunn D, Raifer H, Picard F, Zhang Y, Winter H, Guenther S, Weigert A, Weigmann B, Dumoutier L, Renauld JC, Waisman A, Schmall A, Tufman A, Fink L, Brüne B, Bopp T, Grimminger F, Seeger W, Pullamsetti SS, Huber M, Savai R

J Clin Invest 2020 Jul 1;130(7):3560-3575. doi: 10.1172/JCI124037

Nuclear pore protein Nup98 is involved in replication of Rift Valley fever virus and nuclear import of virulence factor NSs

Lau S, Weber F

J Gen Virol 2020 Jul;101(7):712-716. doi: 10.1099/jgv.0.001347

Suppression of p38-MAPK endows endoderm propensity to human embryonic stem cells

Taei A, Samadian A, Ghezel-Ayagh Z, Mollamohammadi S, Moradi S, Kiani T, Janzamin E, Farzaneh Z, Tahamtani Y, Braun T, Hassani SN, Baharvand H

Biochem Biophys Res Commun 2020 Jun 30;527(3):811-817. doi: 10.1016/j.bbrc.2020.04.119

Blood Levels of Free-Circulating Mitochondrial DNA in Septic Shock and Postsurgical Systemic Inflammation and Its Influence on Coagulation: A Secondary Analysis of a Prospective Observational Study

Schneck E, Edinger F, Hecker M, Sommer N, Pak O, Weissmann N, Hecker A, Reichert M, Markmann M, Sander M, Koch C

J Clin Med 2020 Jun 30;9(7):2056. doi: 10.3390/jcm9072056

Immunomodulation by an Omega-6 Fatty Acid Reduced Mixed Lipid Emulsion in Murine Acute Respiratory Distress Syndrome

Hecker M, Rose M, Hecker A, Dietrich H, Schaefer MB, Sommer N, Seeger W, Mayer K

J Clin Med 2020 Jun 29;9(7):2048. doi: 10.3390/jcm9072048

Associations of oxygenated hemoglobin with disease burden and prognosis in stable COPD: Results from COSYCONET

Trudzinski FC, Jörres RA, Alter P, Kahnert K, Waschki B, Herr C, Kellerer C, Omlor A, Vogelmeier CF, Fähndrich S, Watz H, Welte T, Jany B, Söhler S, Biertz F, Herth F, Kauczor HU, Bals R; COSYCONET consortium

Sci Rep 2020 Jun 29;10(1):10544. doi: 10.1038/s41598-020-67197-x