KFO309 - The clinical research unit Virus Induced Lung injury

All Publications

Evidence for the critical role of the PI3K signaling pathway in particulate matter-induced dysregulation of the inflammatory mediators COX-2/PGE2 and the associated epithelial barrier protein Filaggrin in the bronchial epithelium

Song C, Liu L, Chen J, Hu Y, Li J, Wang B, Bellusci S, Chen C, Dong N

Cell Biol Toxicol 2020 Aug;36(4):301-313. doi: 10.1007/s10565-019-09508-1

Publisher Correction: Whole-genome sequencing of a sporadic primary immunodeficiency cohort

Thaventhiran JED, Lango Allen H, Burren OS, Rae W, Greene D, Staples E, Zhang Z, Farmery JHR, Simeoni I, Rivers E, Maimaris J, Penkett CJ, Stephens J, Deevi SVV, Sanchis-Juan A, Gleadall NS, Thomas MJ, Sargur RB, Gordins P, Baxendale HE, Brown M, Tuijnenburg P, Worth A, Hanson S, Linger RJ, Buckland MS, Rayner-Matthews PJ, Gilmour KC, Samarghitean C, Seneviratne SL, Sansom DM, Lynch AG, Megy K, Ellinghaus E, Ellinghaus D, Jorgensen SF, Karlsen TH, Stirrups KE, Cutler AJ, Kumararatne DS, Chandra A, Edgar JDM, Herwadkar A, Cooper N, Grigoriadou S, Huissoon AP, Goddard S, Jolles S, Schuetz C, Boschann F; Primary Immunodeficiency Consortium for the NIHR Bioresource; Lyons PA, Hurles ME, Savic S, Burns SO, Kuijpers TW, Turro E, Ouwehand WH, Thrasher AJ, Smith KGC

Nature 2020 Aug;584(7819):E2. doi: 10.1038/s41586-020-2556-6

Laboratory characteristics of patients infected with the novel SARS-CoV-2 virus

Skevaki C, Fragkou PC, Cheng C, Xie M, Renz H

J Infect 2020 Aug;81(2):205-212. doi: 10.1016/j.jinf.2020.06.039

Ruxolitinib for the treatment of SARS-CoV-2 induced acute respiratory distress syndrome (ARDS)

Neubauer A, Wiesmann T, Vogelmeier CF, Mack E, Skevaki C, Gaik C, Keller C, Figiel J, Sohlbach K, Rolfes C, Renz H, Wulf H, Burchert A

Leukemia 2020 Aug;34(8):2276-2278. doi: 10.1038/s41375-020-0907-9

The A-to-I RNA Editing Enzyme Adar1 Is Essential for Normal Embryonic Cardiac Growth and Development

Moore JB 4th, Sadri G, Fischer AG, Weirick T, Militello G, Wysoczynski M, Gumpert AM, Braun T, Uchida S

Circ Res 2020 Jul 31;127(4):550-552. doi: 10.1161/CIRCRESAHA.120.316932

Isoform-specific characterization of class I histone deacetylases and their therapeutic modulation in pulmonary hypertension

Chelladurai P, Dabral S, Basineni SR, Chen CN, Schmoranzer M, Bender N, Feld C, Nötzold RR, Dobreva G, Wilhelm J, Jungblut B, Zhao L, Bauer UM, Seeger W, Pullamsetti SS

Sci Rep 2020 Jul 30;10(1):12864. doi: 10.1038/s41598-020-69737-x

SirT7 auto-ADP-ribosylation regulates glucose starvation response through mH2A1

Simonet NG, Thackray JK, Vazquez BN, Ianni A, Espinosa-Alcantud M, Morales-Sanfrutos J, Hurtado-Bagès S, Sabidó E, Buschbeck M, Tischfield J, De La Torre C, Esteller M, Braun T, Olivella M, Serrano L, Vaquero A

Sci Adv 2020 Jul 24;6(30):eaaz2590. doi: 10.1126/sciadv.aaz2590

Recognition of breathprints of lung cancer and chronic obstructive pulmonary disease using the Aeonose® electronic nose

Krauss E, Haberer J, Barreto G, Degen M, Seeger W, Guenther A

J Breath Res 2020 Jul 24;14(4):046004. doi: 10.1088/1752-7163/ab8c50

Randomized, Blinded, Dose-Ranging Trial of an Ebola Virus Glycoprotein Nanoparticle Vaccine With Matrix-M Adjuvant in Healthy Adults

Fries L, Cho I, Krähling V, Fehling SK, Strecker T, Becker S, Hooper JW, Kwilas SA, Agrawal S, Wen J, Lewis M, Fix A, Thomas N, Flyer D, Smith G, Glenn G

J Infect Dis 2020 Jul 23;222(4):572-582. doi: 10.1093/infdis/jiz518. PMID: 31603201

TMPRSS2 and furin are both essential for proteolytic activation of SARS-CoV-2 in human airway cells

Bestle D, Heindl MR, Limburg H, Van Lam van T, Pilgram O, Moulton H, Stein DA, Hardes K, Eickmann M, Dolnik O, Rohde C, Klenk HD, Garten W, Steinmetzer T,

Böttcher-Friebertshäuser E

Life Sci Alliance 2020 Jul 23;3(9):e202000786. doi: 10.26508/lsa.202000786

Impact of SARS-CoV-2 pandemic on pulmonary hypertension out-patient clinics in Germany: a multi-centre study

Yogeswaran A, Gall H, Tello K, Grünig E, Xanthouli P, Ewert R, Kamp JC, Olsson KM, Wißmüller M, Rosenkranz S, Klose H, Harbaum L, Lange TJ, Opitz CF, Waelde A, Milger K, Sommer N, Seeger W, Ghofrani HA, Richter MJ

Pulm Circ 2020 Jul 23;10(3):2045894020941682. doi: 10.1177/2045894020941682

Fibroblast Growth Factor-14 Acts as Tumor Suppressor in Lung Adenocarcinomas

Turkowski K, Herzberg F, Günther S, Brunn D, Weigert A, Meister M, Muley T, Kriegsmann M, Schneider MA, Winter H, Thomas M, Grimminger F, Seeger W, Savai Pullamsetti S, Savai R

Cells 2020 Jul 22;9(8):1755. doi: 10.3390/cells9081755

Ebola Virus Nucleocapsid-Like Structures Utilize Arp2/3 Signaling for Intracellular Long-Distance Transport

Grikscheit K, Dolnik O, Takamatsu Y, Pereira AR, Becker S

Cells 2020 Jul 19;9(7):1728. doi: 10.3390/cells9071728

Bacterial colonization within the first 6 weeks of life and pulmonary outcome in preterm infants

Lauer T, Behnke J, Oehmke F, Baecker J, Gentil K, Chakraborty T, Schloter M, Gertheiss J, Ehrhardt H

J Clin Med 2020 Jul 15;9(7):2240. doi: 10.3390/jcm9072240

eIF2B as a Target for Viral Evasion of PKR-Mediated Translation Inhibition

Wuerth JD, Habjan M, Kainulainen M, Berisha B, Bertheloot D, Superti-Furga G, Pichlmair A, Weber F

mBio 2020 Jul 14;11(4):e00976-20. doi: 10.1128/mBio.00976-20