KFO309 - The clinical research unit Virus Induced Lung injury

All Publications

miRNA142-3p targets Tet2 and impairs Treg differentiation and stability in models of type 1 diabetes

Scherm MG, Serr I, Zahm AM, Schug J, Bellusci S, Manfredini R, Salb VK, Gerlach K, Weigmann B, Ziegler AG, Kaestner KH, Daniel C

Nat Commun 2019 Dec 13;10(1):5697. doi: 10.1038/s41467-019-13587-3

Recent advances in our understanding of the mechanisms of lung alveolarization and bronchopulmonary dysplasia

Lignelli E, Palumbo F, Myto D, Morty RE

Am J Physiol Lung Cell Mol Physiol 2019 Dec 1;317(6):L832-L887

The Oncogene ECT2 Contributes to a Hyperplastic, Proliferative Lung Epithelial Cell Phenotype in Idiopathic Pulmonary Fibrosis

Ulke HM, Mutze K, Lehmann M, Wagner DE, Heinzelmann K, Günther A, Eickelberg O, Königshoff M

Am J Respir Cell Mol Biol 2019 Dec;61(6):713-726. doi: 10.1165/rcmb.2019-0047OC

Reply to Bogaard et al.: Emphysema Is-at the Most-Only a Mild Phenotype in the Sugen/Hypoxia Rat Model of Pulmonary Arterial Hypertension

Kojonazarov B, Hadzic S, Ghofrani HA, Grimminger F, Seeger W, Weissmann N, Schermuly RT

Am J Respir Crit Care Med 2019 Dec 1;200(11):1450-1452. doi: 10.1164/rccm.201907-1367LE

Impaired right ventricular lusitropy is associated with ventilatory inefficiency in pulmonary arterial hypertension

Tello K, Dalmer A, Vanderpool R, Ghofrani HA, Naeije R, Roller F, Seeger W, Dumitrescu D, Sommer N, Brunst A, Gall H, Richter MJ

Eur Respir J 2019 Nov 21;54(5):1900342. doi: 10.1183/13993003.00342-2019

The CalcR-PKA-Yap1 Axis Is Critical for Maintaining Quiescence in Muscle Stem Cells

Zhang L, Noguchi YT, Nakayama H, Kaji T, Tsujikawa K, Ikemoto-Uezumi M, Uezumi A, Okada Y, Doi T, Watanabe S, Braun T, Fujio Y, Fukada SI

Cell Rep 2019 Nov 19;29(8):2154-2163.e5. doi: 10.1016/j.celrep.2019.10.057

Structure and function of the Toscana virus cap-snatching endonuclease

Jones R, Lessoued S, Meier K, Devignot S, Barata-García S, Mate M, Bragagnolo G, Weber F, Rosenthal M, Reguera J

Nucleic Acids Res 2019 Nov 18;47(20):10914-10930. doi: 10.1093/nar/gkz838

WNT/RYK signaling restricts goblet cell differentiation during lung development and repair

Kim HT, Yin W, Nakamichi Y, Panza P, Grohmann B, Buettner C, Guenther S, Ruppert C, Kobayashi Y, Guenther A, Stainier DYR

PNAS 2019 116 (51) 25697-25706. doi.org/10.1073/pnas.1911071116

The association of cognitive functioning as measured by the DemTect with functional and clinical characteristics of COPD: results from the COSYCONET cohort

von Siemens SM, Perneczky R, Vogelmeier CF, Behr J, Kauffmann-Guerrero D, Alter P, Trudzinski FC, Bals R, Grohé C, Söhler S, Waschki B, Lutter JI, Welte T, Jörres RA, Kahnert K; COSYCONET study group

Respir Res 2019 Nov 14;20(1):257. doi: 10.1186/s12931-019-1217-5

Humoral Immunogenicity and Efficacy of a Single Dose of ChAdOx1 MERS Vaccine Candidate in Dromedary Camels

Alharbi NK, Qasim I, Almasoud A, Aljami HA, Alenazi MW, Alhafufi A, Aldibasi OS, Hashem AM, Kasem S, Albrahim R, Aldubaib M, Almansour A, Temperton NJ, Kupke A, Becker S, Abu-Obaidah A, Alkarar A, Yoon IK, Azhar E, Lambe T, Bayoumi F, Aldowerij A, Ibrahim OH, Gilbert SC, Balkhy HH

Sci Rep 2019 Nov 8;9(1):16292. doi: 10.1038/s41598-019-52730-4

Distinct IL-1a-responsive enhancers promote acute and coordinated changes in chromatin topology in a hierarchical manner

Weiterer SS, Meier‐Soelch J, Georgomanolis T,  Mizi A, Beyerlein A, Weiser H,  Brant L, Mayr‐Buro C, Jurida L, Beuerlein K, Müller H,  Weber A, Tenekeci U, Dittrich‐Breiholz O, Bartkuhn M,  Nist A, Stiewe T, van IJcken WF, Riedlinger T, Schmitz ML,  Papantonis A, Kracht M

The EMBO Journal 2020, 39:e101533

Doppler-Derived Renal Venous Stasis Index in the Prognosis of Right Heart Failure

Husain-Syed F, Birk HW, Ronco C, Schörmann T, Tello K, Richter MJ, Wilhelm J, Sommer N, Steyerberg E, Bauer P, Walmrath HD, Seeger W, McCullough PA, Gall H, Ghofrani HA

J Am Heart Assoc 2019 Nov 5;8(21):e013584. doi: 10.1161/JAHA.119.013584

RNA-DNA hybrids and ssDNA differ in intracellular half-life and toll-like receptor 9 activation

Obermann HL, Eberhardt I, Yu P, Kaufmann A, Bauer S

Immunobiology 2019 Nov;224(6):843-851. doi: 10.1016/j.imbio.2019.08.001

A functional variant in the miR-142 promoter modulating its expression and conferring risk of Alzheimer disease

Ghanbari M, Munshi ST, Ma B, Lendemeijer B, Bansal S, Adams HH, Wang W, Goth K, Slump DE, van den Hout MCGN, van IJcken WFJ, Bellusci S, Pan Q, Erkeland SJ, de Vrij FMS, Kushner SA, Ikram MA

Hum Mutat 2019 Nov;40(11):2131-2145. doi: 10.1002/humu.23872

Exploration of Physiological and Pathophysiological Implications of miRNA-143 and miRNA-145 in Cerebral Arteries

Christensen ST, Johansson SE, Warfvinge K, Braun T, Boettger T, Edvinsson L, Haanes KA

J Cardiovasc Pharmacol 2019 Nov;74(5):409-419. doi: 10.1097/FJC.0000000000000735