KFO309 - The clinical research unit Virus Induced Lung injury

All Publications

Severe COVID-19 Is Marked by a Dysregulated Myeloid Cell Compartment

Schulte-Schrepping J, Reusch N, Paclik D, Baßler K, Schlickeiser S, Zhang B, Krämer B, Krammer T, Brumhard S, Bonaguro L, De Domenico E, Wendisch D, Grasshoff M, Kapellos TS, Beckstette M, Pecht T, Saglam A, Dietrich O, Mei HE, Schulz AR, Conrad C, Kunkel D, Vafadarnejad E, Xu CJ, Horne A, Herbert M, Drews A, Thibeault C, Pfeiffer M, Hippenstiel S, Hocke A, Müller-Redetzky H, Heim KM, Machleidt F, Uhrig A, Bosquillon de Jarcy L, Jürgens L, Stegemann M, Glösenkamp CR, Volk HD, Goffinet C, Landthaler M, Wyler E, Georg P, Schneider M, Dang-Heine C, Neuwinger N, Kappert K, Tauber R, Corman V, Raabe J, Kaiser KM, Vinh MT, Rieke G, Meisel C, Ulas T, Becker M, Geffers R, Witzenrath M, Drosten C, Suttorp N, von Kalle C, Kurth F, Händler K, Schultze JL, Aschenbrenner AC, Li Y, Nattermann J, Sawitzki B, Saliba AE, Sander LE; Deutsche COVID-19 OMICS Initiative (DeCOI)

Cell 2020 Sep 17;182(6):1419-1440.e23. doi: 10.1016/j.cell.2020.08.001

Cellular Gene Expression during Hepatitis C Virus Replication as Revealed by Ribosome Profiling

Gerresheim GK, Bathke J, Michel AM, Andreev DE, Shalamova LA, Rossbach O, Hu P, Glebe D, Fricke M, Marz M, Goesmann A, Kiniry SJ, Baranov PV, Shatsky IN, Niepmann M

Int J Mol Sci 2019 Mar 15;20(6):1321. doi: 10.3390/ijms20061321

ASA3P: An automatic and scalable pipeline for the assembly, annotation and higher-level analysis of closely related bacterial isolates

Schwengers O, Hoek A, Fritzenwanker M, Falgenhauer L, Hain T, Chakraborty T, Goesmann A

PLoS Comput Biol 2020 Mar 5;16(3):e1007134. doi: 10.1371/journal.pcbi.1007134

Shielding the mRNA-translation factor eIF2B from inhibitory p-eIF2 as a viral strategy to evade protein kinase R-mediated innate immunity

Wuerth JD, Weber F

Curr Opin Immunol 78:102251. doi: 10.1016/j.coi.2022.102251

A universal SARS-CoV DNA vaccine inducing highly cross-reactive neutralizing antibodies and T cells

Appelberg S, Ahlén G, Yan J, Nikouyan N, Weber S, Larsson O, Höglund U, Aleman S, Weber F, Perlhamre E, Apro J, Gidlund EK, Tuvesson O, Salati S, Cadossi M, Tegel H, Hober S, Frelin L, Mirazimi A, Sällberg M

EMBO Mol Med Oct 10;14(10):e15821. doi: 10.15252/emmm.202215821

Long-term comprehensive cardiopulmonary phenotyping of COVID-19

Kimmig LM, Rako ZA, Ziegler S, Richter MJ, G S AT, Roller F, Grimminger F, Vadász I, Seeger W, Herold S, Tello K, Matt U

Respir Res 2022 Sep 21;23(1):263. doi: 10.1186/s12931-022-02173-9

The German National Pandemic Cohort Network (NAPKON): rationale, study design and baseline characteristics

Schons M, Pilgram L, Reese JP, Stecher M, Anton G, Appel KS, Bahmer T, Bartschke A, Bellinghausen C, Bernemann I, Brechtel M, Brinkmann F, Brünn C, Dhillon C, Fiessler C, Geisler R, Hamelmann E, Hansch S, Hanses F, Hanß S, Herold S, Heyder R, Hofmann AL, Hopff SM, Horn A, Jakob C, Jiru-Hillmann S, Keil T, Khodamoradi Y, Kohls M, Kraus M, Krefting D, Kunze S, Kurth F, Lieb W, Lippert LJ, Lorbeer R, Lorenz-Depiereux B, Maetzler C, Miljukov O, Nauck M, Pape D, Püntmann V, Reinke L, Römmele C, Rudolph S, Sass J, Schäfer C, Schaller J, Schattschneider M, Scheer C, Scherer M, Schmidt S, Schmidt J, Seibel K, Stahl D, Steinbeis F, Störk S, Tauchert M, Tebbe JJ, Thibeault C, Toepfner N, Ungethüm K, Vadasz I, Valentin H, Wiedmann S, Zoller T, Nagel E, Krawczak M, von Kalle C, Illig T, Schreiber S, Witzenrath M, Heuschmann P, Vehreschild JJ; NAPKON Research Group

Eur J Epidemiol 2022 Aug;37(8):849-870. doi: 10.1007/s10654-022-00896-z

Identification of SARS-CoV-2-induced pathways reveals drug repurposing strategies

Han N, Hwang W, Tzelepis K, Schmerer P, Yankova E, MacMahon M, Lei W, M Katritsis N, Liu A, Felgenhauer U, Schuldt A, Harris R, Chapman K, McCaughan F, Weber F, Kouzarides T

Am Sci Adv 2021 Jun 30;7(27):eabh3032. doi: 10.1126/sciadv.abh3032

What goes around comes around: Artificial circular RNAs bypass cellular antiviral responses

Breuer J

Mol Ther Nucleic Acids 2022 28:623-635 doi.10.1016/j.omtn.2022.04.017

FGF10 triggers de novo alveologenesis in a BPD model: impact on the resident mesenchymal niche cells

Taghizadeh S, Chao C-M, Guenther S, Glaser L, Gersmann L, Michel G, Kraut S, Goth K, Koepke J, Heiner M, Vazquez-Armendariz AI, Herold S, Samakovlis C, Weissmann N, Ricci F, Aquila G, Boyer L, Erhardt H, Minoo P, Bellusci S, Rivetti S

Stem Cells 2022 Apr 19 sxac025. doi: 10.1093/stmcls/sxac025

Fgfr2b signaling is essential for the maintenance of the alveolar epithelial type 2 lineage during lung homeostasis in mice

Ahmadvand N, Lingampally A, Khosravi F, Vazquez-Armendariz I, Rivetti S, Jones MR, Wilhelm J, Herold S, Barreto G, Koepke J, Samakovlis C, Carraro G, Zhang J-S, Al Alam D, Bellusci S

Cell Mol Life Sci 2022 19;79(6):302. doi: 10.1007/s00018-022-04327-w

Editorial: Elevated Carbon Dioxide Sensing and Physiologic Effects

Cummins EP, Bharat A, Sznajder JI, Vadász I

Front Physiol 2022 Apr 27;13:894222. doi: 10.3389/fphys.2022.894222

Thapsigargin: key to new host-directed coronavirus antivirals?

Shaban MS, Mayr-Buro C, Meier-Soelch, Albert BV, Schmitz ML, Ziebuhr J, Kracht M

TIPS 2022 doi.10.1016/j.tips.2022.04.004

Cyclosporin A Reveals Potent Antiviral Effects in Preclinical Models of SARS-CoV-2 Infection

Sauerhering L, Kuznetsova I, Kupke A, Meier L, Halwe S, Rohde C, Schmidt J, Morty RE, Danov O, Braun A, Vadász I, Becker B, Herold S

Am J Respir Crit Care 2022 Apr 15;205(8):964-968. doi: 10.1164/rccm.202108-1830LE

3D In Vitro Models: Novel Insights into Idiopathic Pulmonary Fibrosis Pathophysiology and Drug Screening

Vazquez-Armendariz AI, Barroso MM, El Agha E, Herold, S

Cells 11 (9):1526 doi.org/10.3390/cells11091526