KFO309 - The clinical research unit Virus Induced Lung injury

All Publications

Liver stiffness is associated with right heart dysfunction, cardiohepatic syndrome, and prognosis in pulmonary hypertension

Rako ZA, Yogeswaran A, Yildiz S, Weidemann P, Zedler D, da Rocha BB, Kryvenko V, Schäfer S, Ghofrani HA, Seeger W, Kremer NC, Tello K

J Heart Lung Transplant 2024 Jul;43(7):1105-1115. doi: 10.1016/j.healun.2024.02.013

Right ventricular pressure-strain relationship-derived myocardial work reflects contractility: Validation with invasive pressure-volume analysis

Lakatos BK, Rako Z, Szijártó Á, da Rocha BRB, Richter MJ, Fábián A, Gall H, Ghofrani HA, Kremer N, Seeger W, Zedler D, Yildiz S, Yogeswaran A, Merkely B, Tello K, Kovács A

J Heart Lung Transplant 2024 Jul;43(7):1183-1187. doi: 10.1016/j.healun.2024.03.007

Microscopic computed tomography with AI-CNN-powered image analysis: the path to phenotype bleomycin-induced lung injury

Henneke I, Pilz C, Wilhelm J, Alexopoulos I, Ezaddoustdar A, Mukhametshina R, Weissmann N, Ghofrani HA, Grimminger F, Seeger W, Schermuly RT, Wygrecka M, Kojonazarov B

Am J Physiol Cell Physiol 2024 Jun 1;326(6):C1637-C1647. doi: 10.1152/ajpcell.00708.2023

Physiological mechanisms behind respiratory variations in right atrial pressure in pulmonary hypertension

Yogeswaran A, da Rocha BB, Rako ZA, Kaufmann SJ, Schäfer S, Kremer N, Ghofrani HA, Seeger W, Tello K

Sci Rep 2024 May 31;14(1):12547. doi: 10.1038/s41598-024-61825-6

Native hepatic T1-time as a non-invasive predictor of diastolic dysfunction and a monitoring tool for disease progression and treatment response in patients with pulmonary hypertension

Kremer N, Roller FC, Kremer S, Schäfer S, Kryvenko V, Rako ZA, Brito da Rocha BR, Yogeswaran A, Seeger W, Guth S, Wiedenroth CB, Tello K

Int J Cardiol 2024 May 16;409:132189. doi: 10.1016/j.ijcard.2024.132189

The diverging roles of insulin-like growth factor binding proteins in pulmonary arterial hypertension

Schlueter BC, Quanz K, Baldauf J, Petrovic A, Ruppert C, Guenther A, Gall H, Tello K, Grimminger F, Ghofrani HA, Weissmann N, Seeger W, Schermuly RT, Weiss A

Vascul Pharmacol 2024 May 16;155:107379. doi: 10.1016/j.vph.2024.107379

WSB1, a Hypoxia-Inducible E3 Ligase, Promotes Myofibroblast Accumulation and Attenuates Alveolar Epithelial Regeneration in Mouse Lung Fibrosis

Chong L, Zou L, Xiang L, Song X, Miao W, Yan X, Xu M, Ling G, El Agha E, Bellusci S, Lou Z, Zhang H, Zhang JS

Am J Pathol 2024 May;194(5):656-672. doi: 10.1016/j.ajpath.2024.01.010

Precision cardiac monitoring: algorithmic real-time assessment of right ventricular function in pulmonary hypertension

Kremer N, Glocker F, Schäfer S, Rako Z, Yogeswaran A, Seeger W, Hopf HB, Tello K

ESC Heart Fail 2024 Apr 30. doi: 10.1002/ehf2.14833

ACE2 acts as a novel regulator of TMPRSS2-catalyzed proteolytic activation of influenza A virus in airway cells

Heindl MR, Rupp A-L, Schwerdtner M, Bestle D, Harbig A, De Rocher A, Schmacke LC, Staker B, Steinmetzer T, Stein DA, Moulton HM, Böttcher-Friebertshäuser E

J Virol 2024 Apr 16;98(4):e0010224. doi: 10.1128/jvi.00102-24

Effects of liberalising visiting policy and staff education on parental visiting duration in the neonatal unit

Schuler R, Frodermann T, Waitz M, Hahn A, Ehrhardt H, Neubauer BA, Mihatsch WA

Acta Paediatr 2024 Apr;113(4):684-691. doi: 10.1111/apa.17106

miR-147b mediated suppression of DUSP8 promotes lung cancer progression

Turkowski K, Herzberg F, Günther S, Weigert A, Haselbauer T, Fink L, Brunn D, Grimminger F, Seeger W, Sültmann H, Stiewe T, Pullamsetti SS, Savai R

Oncogene 2024 Apr;43(16):1178-1189. doi: 10.1038/s41388-024-02969-7

Phosphatidylserine-exposing extracellular vesicles in body fluids are an innate defence against apoptotic mimicry viral pathogens

Groß R, Reßin H, von Maltitz P, Albers D, Schneider L, Bley H, Hoffmann M, Cortese M, Gupta D, Deniz M, Choi JY, Jansen J, Preußer C, Seehafer K, Pöhlmann S, Voelker DR, Goffinet C, Pogge-von Strandmann E, Bunz U, Bartenschlager R, El Andaloussi S, Sparrer KMJ, Herker E, Becker S, Kirchhoff F, Münch J, Müller JA

Nat Microbiol 2024 Apr;9(4):905-921. doi: 10.1038/s41564-024-01637-6

Crimean-Congo haemorrhagic fever virus uses LDLR to bind and enter host cells

Monteil VM, Wright SC, Dyczynski M, Kellner MJ, Appelberg S, Platzer SW, Ibrahim A, Kwon H, Pittarokoilis I, Mirandola M, Michlits G, Devignot S, Elder E, Abdurahman S, Bereczky S, Bagci B, Youhanna S, Aastrup T, Lauschke VM, Salata C, Elaldi N, Weber F, Monserrat N, Hawman DW, Feldmann H, Horn M, Penninger JM, Mirazimi A

Nat Microbiol 2024 Mar 28. doi: 10.1038/s41564-024-01672-3

Influenza A virus replicates productively in primary human kidney cells and induces factors and mechanisms related to regulated cell death and renal pathology observed in virus-infected patients

Koch B, Shehata M, Müller-Ruttloff C, Gouda SA, Wetzstein N, Patyna S, Scholz A, Schmid T, Dietrich U, Münch C, Ziebuhr J, Geiger H, Martinez-Sobrido L, Baer PC, Mostafa A, Pleschka S

Front Cell Infect Microbiol 2024 Mar 25;14:1363407. doi: 10.3389/fcimb.2024.1363407

A type I interferon regulatory network for human plasmacytoid dendritic cells based on heparin, membrane-bound and soluble BDCA-2

Venegas-Solis F, Staliunaite L, Rudolph E, Münch CC, Yu P, Freibert SA, Maeda T, Zimmer CL, Möbs C, Keller C, Kaufmann A, Bauer S

Proc Natl Acad Sci U S A 2024 Mar 19;121(12):e2312404121. doi: 10.1073/pnas.2312404121