KFO309 - The clinical research unit Virus Induced Lung injury

All Publications

Crimean-Congo haemorrhagic fever virus uses LDLR to bind and enter host cells

Monteil VM, Wright SC, Dyczynski M, Kellner MJ, Appelberg S, Platzer SW, Ibrahim A, Kwon H, Pittarokoilis I, Mirandola M, Michlits G, Devignot S, Elder E, Abdurahman S, Bereczky S, Bagci B, Youhanna S, Aastrup T, Lauschke VM, Salata C, Elaldi N, Weber F, Monserrat N, Hawman DW, Feldmann H, Horn M, Penninger JM, Mirazimi A

Nat Microbiol 2024 Mar 28. doi: 10.1038/s41564-024-01672-3

Influenza A virus replicates productively in primary human kidney cells and induces factors and mechanisms related to regulated cell death and renal pathology observed in virus-infected patients

Koch B, Shehata M, Müller-Ruttloff C, Gouda SA, Wetzstein N, Patyna S, Scholz A, Schmid T, Dietrich U, Münch C, Ziebuhr J, Geiger H, Martinez-Sobrido L, Baer PC, Mostafa A, Pleschka S

Front Cell Infect Microbiol 2024 Mar 25;14:1363407. doi: 10.3389/fcimb.2024.1363407

A type I interferon regulatory network for human plasmacytoid dendritic cells based on heparin, membrane-bound and soluble BDCA-2

Venegas-Solis F, Staliunaite L, Rudolph E, Münch CC, Yu P, Freibert SA, Maeda T, Zimmer CL, Möbs C, Keller C, Kaufmann A, Bauer S

Proc Natl Acad Sci U S A 2024 Mar 19;121(12):e2312404121. doi: 10.1073/pnas.2312404121

Comparison of Contemporary Risk Scores in All Groups of Pulmonary Hypertension: A Pulmonary Vascular Research Institute GoDeep Meta-Registry Analysis

Yogeswaran A, Gall H, Fünderich M, Wilkins MR, Howard L, Kiely DG, Lawrie A, Hassoun PM, Sirenklo Y, Torbas O, Sweatt AJ, Zamanian RT, Williams PG, Frauendorf M, Arvanitaki A, Giannakoulas G, Saleh K, Sabbour H, Cajigas HR, Frantz R, Al Ghouleh I, Chan SY, Brittain E, Annis JS, Pepe A, Ghio S, Orfanos S, Anthi A, Majeed RW, Wilhelm J, Ghofrani HA, Richter MJ, Grimminger F, Sahay S, Tello K, Seeger W; Pulmonary Vascular Research Institute GoDeep Consortium

Chest 2024 Mar 19:S0012-3692(24)00309-X. doi: 10.1016/j.chest.2024.03.018

pH inactivation of SARS-CoV-2 and SARS-CoV in virus spiked protein A eluates from a mAb purification process

Limburg H, Schwerdtner M, Wilson E, Roth B, Cassart JP, Werner AD, Harbig A, Böttcher-Friebertshäuser E, Stokes A

Biologicals 2024 Mar 14;86:101753. doi: 10.1016/j.biologicals.2024.101753

Alveolar-capillary endocytosis and trafficking in acute lung injury and acute respiratory distress syndrome

Kryvenko V, Vadász I

Front Immunol 2024 Mar 12;15:1360370. doi: 10.3389/fimmu.2024.1360370

Adaptive multi-interventional trial platform to improve patient care for fibrotic interstitial lung diseases

Kawano-Dourado L, Kulkarni T, Ryerson CJ, Rivera-Ortega P, Baldi BG, Chaudhuri N, Funke-Chambour M, Hoffmann-Vold AM, Johannson KA, Khor YH, Montesi SB, Piccari L, Prosch H, Molina-Molina M, Sellares Torres J, Bauer-Ventura I, Rajan S, Jacob J, Richards D, Spencer LG, Wendelberger B, Jensen T, Quintana M, Kreuter M, Gordon AC, Martinez FJ, Kaminski N, Cornelius V, Lewis R, Adams W, Jenkins G; REMAP-ILD consortium

Thorax 2024 Mar 6:thorax-2023-221148. doi: 10.1136/thorax-2023-221148

Disease trajectories in interstitial lung diseases - data from the EXCITING-ILD registry

Buschulte K, Kabitz HJ, Hagmeyer L, Hammerl P, Esselmann A, Wiederhold C, Skowasch D, Stolpe C, Joest M, Veitshans S, Höffgen M, Maqhuzu P, Schwarzkopf L, Hellmann A, Pfeifer M, Behr J, Karpavicius R, Günther A, Polke M, Höger P, Somogyi V, Lederer C, Markart P, Kreuter M

Respir Res 2024 Mar 6;25(1):113. doi: 10.1186/s12931-024-02731-3

SIRT7: a novel molecular target for personalized cancer treatment?

Ianni A, Kumari P, Tarighi S, Braun T, Vaquero A

Oncogene 2024 Mar;43(14):993-1006. doi: 10.1038/s41388-024-02976-8

Toward drug-induced heart regeneration

Yuan X, Braun T

Nat Cardiovasc Res 2024 Mar;3(3):260-261. doi: 10.1038/s44161-024-00446-8

Identification of Dual Inhibitors Targeting Main Protease (Mpro) and Cathepsin L as Potential Anti-SARS-CoV-2 Agents

Previti S, Ettari R, Calcaterra E, Roggia M, Natale B, Weldert AC, Müller-Ruttloff C, Salisch F, Irto A, Cigala RM, Ziebuhr J, Schirmeister T, Cosconati S, Zappalà M

ACS Med Chem Lett 2024 Mar 1;15(5):602-609. doi: 10.1021/acsmedchemlett.3c00562

Fragment-Based Design, Synthesis, and Characterization of Aminoisoindole-Derived Furin Inhibitors

Lange RW, Bloch K, Heindl MR, Wollenhaupt J, Weiss MS, Brandstetter H, Klebe G, Falcone FH, Böttcher-Friebertshäuser E, Dahms SO, Steinmetzer T

ChemMedChem 2024 Feb 22:e202400057. doi: 10.1002/cmdc.202400057

Task Force Dyspnoe Unit (DU)

Dellweg D, Nilius G, Grünewaldt A, Günther A, Held M, Hetzel M, Schlesinger A, Schlott R, Sofianos G, Unnewehr M, Voshaar T, Randerath W

Pneumologie 2024 Feb 21. German. doi: 10.1055/a-2238-4253

A MoClo-Compatible Toolbox of ECF Sigma Factor-Based Regulatory Switches for Proteobacterial Chassis

Meier D, Rauch C, Wagner M, Klemm P, Blumenkamp P, Müller R, Ellenberger E, Karia KM, Vecchione S, Serrania J, Lechner M, Fritz G, Goesmann A, Becker A

J Allergy Clin Immunol Pract 2023 Feb;11(2):591-601. doi: 10.1016/j.jaip.2022.10.035

Correction: GABenchToB: A Genome Assembly Benchmark Tuned on Bacteria and Benchtop Sequencers

Jünemann S, Prior K, Albersmeier A, Albaum S, Kalinowski J, Goesmann A, Stoye J, Harmsen D

PLoS One 2024 Feb 15;19(2):e0299269. doi: 10.1371/journal.pone.0299269