KFO309 - The clinical research unit Virus Induced Lung injury

All Publications

Immunoglobulin Deficiency as an Indicator of Disease Severity in Patients with COVID-19

Husain-Syed F, Vadász I, Wilhelm J, Walmrath HD, Seeger W, Birk HW, Jennert B, Dietrich H, Herold S, Trauth J, Tello K, Sander M, Morty RE, Slanina H, Schüttler CG, Ziebuhr J, Kassoumeh S, Ronco C, Ferrari F, Warnatz K, Stahl K, Seeliger B, Hoeper MM, Welte T, David S

Am J Physiol Lung Cell Mol 2020 Nov 25. doi 10.1152/ajplung.00359.2020

Assessing the effectiveness of pirfenidone in idiopathic pulmonary fibrosis: Long-term, real-world data from european IPF registry (eurIPFreg)

Krauss E, Tello S, Wilhelm J, Schmidt J, Stoehr M, Seeger W, Dartsch RC, Crestani B, Guenther A

J Clin Med 2020 Nov 22;9(11):3763. doi: 10.3390/jcm9113763.

Extracorporeal Carbon Dioxide Removal Using a Renal Replacement Therapy Platform to Enhance Lung-Protective Ventilation in Hypercapnic Patients With Coronavirus Disease 2019-Associated Acute Respiratory Distress Syndrome

Husain-Syed F, Birk HW, Wilhelm J, Ronco C, Ranieri VM, Karle B, Kuhnert S, Tello K, Hecker M, Morty RE, Herold S, Kehl O, Walmrath HD, Seeger W, Vadász I

Front Med 2020 Nov 12;7:598379. doi: 10.3389/fmed.2020.598379

Severe organising pneumonia following COVID-19

Vadász I, Husain-Syed F, Dorfmüller P, Roller FC, Tello K, Hecker M, Morty RE, Gattenlöhner S, Walmrath HD, Grimminger F, Herold S, Seeger W

Thorax 2020 Nov 11;thorayjnl-2020-216088. doi: 10.1136/thoraxjnl-2020-216088

A ribosomal RNA fragment with 2',3'-cyclic phosphate and GTP-binding activity acts as RIG-I ligand

Jung S, von Thülen T, Yang I, Laukemper V, Rupf B, Janga H, Panagiotidis GD, Schoen A, Nicolai M, Schulte LN, Obermann HL, Weber F, Kaufmann A, Bauer S.

Nucleic Acid Res 2020 Oct 9;48(18):10397-10412. doi: 10.1093/nar/gkaa739

Inhibition of SARS-CoV-2 by type I and type III interferons

Felgenhauer U, Schoen A, Gad HH, Hartmann R, Schaubmar AR, Failing K, Drosten C, Weber F

J Biol Chem Oct 9;295(41):13958-13964. doi: 10.1074/jbc.AC120.013788

Minoxidil Cannot Be Used To Target Lysyl Hydroxylases during Postnatal Mouse Lung Development: A Cautionary Note

Pfeffer T, Lignelli E, Inoue H, Mižíková I, Surate Solaligue DE, Steenbock H, Myti D, Vadász I, Herold S, Seeger W, Brinckmann J, Morty RE

J Pharmacol Exp Ther 2020 Dec; 375(3):478-487. doi: 10.1124/jpet.120.000138

Multilineage murine stem cells generate complex organoids to model distal lung development and disease

Vazquez‐Armendariz AI, Heiner M, El Agha E, Salwig I, Hoek A, Hessler MC, Shalashova I, Amit Shrestha A, Carraro G, Mengel JP, Günther A, Morty RE, Vadász I, Schwemmle M, Kummer W, Hain T, Goesmann A, Bellusci S, Seeger W, Braun T, Herold S,

EMBO J 2020 39:e103476 doi.org/10.15252/embj.2019103476

Elevated FiO2 increases SARS-CoV-2 co-receptor expression in respiratory tract epithelium

Myti D, Gunjak M, Casado F, Khaghani Raziabad S, Nardiello C, Vadász I, Herold S, Pryhuber G, Seeger W, Morty RE

Am J Physiol Lung Cell Mol Physiol 2020 Oct 1;319(4):L670-L674. doi: 10.1152/ajplung.00345.2020

ATAC-seq footprinting unravels kinetics of transcription factor binding during zygotic genome activation

Bentsen M, Goymann P, Schultheis H, Klee K, Petrova A, Wiegandt R, Fust A, Preussner J, Kuenne C, Braun T, Kim J, Looso M

Nat Commun 2020 Aug 26;11(1):4267. doi: 10.1038/s41467-020-18035-1

Commercially available transfection reagents and negative control siRNA are not inert

Kleefeldt JM, Pozarska A, Nardiello C, Pfeffer T, Vadász I, Herold S, Seeger W, Morty RE

Anal Biochem 2020 Oct 1;606:113828. doi: 10.1016/j.ab.2020.113828

Bacterial colonization within the first 6 weeks of life and pulmonary outcome in preterm infants

Lauer T, Behnke J, Oehmke F, Baecker J, Gentil K, Chakraborty T, Schloter M, Gertheiss J, Ehrhardt H

J Clin Med 2020 Jul 15;9(7):2240. doi: 10.3390/jcm9072240

Acute kidney injury and urinary biomarkers in hospitalized patients with coronavirus disease-2019

Husain-Syed F, Wilhelm J, Kassoumeh S, Birk HW, Herold S, Vadász I, Walmrath HD, Kellum JA, Ronco C, Seeger W

Nephrol Dial Transplant 2020 Jul 1;35(7):1271-1274. doi: 10.1093/ndt/gfaa162

Platon: identification and characterization of bacterial plasmid contigs in short-read draft assemblies exploiting protein sequence-based replicon distribution scores

Schwengers O, Barth P, Falgenhauer L, Hain T, Chakraborty T, Goesmann A

Microbial Genomics 2020 doi 10.1099/mgen.0.000398

Laboratory characteristics of patients infected with the novel SARS-CoV-2 virus

Skevaki C, Fragkou PC, Cheng C, Xie M, Renz H

J Infect 2020 doi.org/10.1016/j.jinf.2020.06.039