KFO309 - The clinical research unit Virus Induced Lung injury

All Publications

Sfrp1 inhibits lung fibroblast invasion during transition to injury-induced myofibroblasts

Mayr CH, Sengupta A, Asgharpour S, Ansari M, Pestoni JC, Ogar P, Angelidis I, Liontos A, Rodriguez-Castillo JA, Lang NJ, Strunz M, Porras-Gonzalez D, Gerckens M, De Sadeleer LJ, Oehrle B, Viteri-Alvarez V, Fernandez IE, Tallquist M, Irmler M, Beckers J, Eickelberg O, Stoleriu GM, Behr J, Kneidinger N, Wuyts WA, Wasnick RM, Yildirim AÖ, Ahlbrecht K, Morty RE, Samakovlis C, Theis FJ, Burgstaller G, Schiller HB

Eur Respir J 2024 Feb 8;63(2):2301326. doi: 10.1183/13993003.01326-2023

Distinct roles of vaccine-induced SARS-CoV-2-specific neutralizing antibodies and T cells in protection and disease

Yan J, Bangalore CR, Nikouyan N, Appelberg S, Silva DN, Yao H, Pasetto A, Weber F, Weber S, Larsson O, Höglund U, Bogdanovic G, Grabbe M, Aleman S, Szekely L, Szakos A, Tuvesson O, Gidlund EK, Cadossi M, Salati S, Tegel H, Hober S, Frelin L, Mirazimi A, Ahlén G, Sällberg M

Mol Ther 2024 Feb 7;32(2):540-555. doi: 10.1016/j.ymthe.2024.01.007

InfluenZing Lung Fibrosis: Reinforcing Endothelial Surface Expression of S1PR1 to Attenuate Post-Acute Respiratory Distress Syndrome Lung Remodeling

Kiliaris G, El Agha E

Am J Respir Cell Mol Biol 2024 Feb;70(2):89-90. doi: 10.1165/rcmb.2023-0372ED

RSV vaccination strategies for high-risk patients 2023: a collaborative position paper by leading German medical societies and organizations

Addo M, Cornely O, Denkinger M, Ertl G, Herold S, Pletz M, Rohde G, Welte T, Windisch W, Witzenrath M.

Infection 2024 Feb;52(1):285-288. doi: 10.1007/s15010-023-02141-5. Epub 2023 Dec 7

Analysis of acute COVID-19 including chronic morbidity: protocol for the deep phenotyping National Pandemic Cohort Network in Germany (NAPKON-HAP)

Steinbeis F, Thibeault C, Steinbrecher S, Ahlgrimm Y, Haack IA, August D, Balzuweit B, Bellinghausen C, Berger S, Chaplinskaya-Sobol I, Cornely O, Doeblin P, Endres M, Fink C, Finke C, Frank S, Hanß S, Hartung T, Hellmuth JC, Herold S, Heuschmann P, Heyckendorf J, Heyder R, Hippenstiel S, Hoffmann W, Kelle SU, Knape P, Koehler P, Kretzler L, Leistner DM, Lienau J, Lorbeer R, Lorenz-Depiereux B, Lüttke CD, Mai K, Merle U, Meyer-Arndt LA, Miljukov O, Muenchhoff M, Müller-Plathe M, Neuhann J, Neuhauser H, Nieters A, Otte C, Pape D, Pinto RM, Pley C, Pudszuhn A, Reuken P, Rieg S, Ritter P, Rohde G, Rönnefarth M, Ruzicka M, Schaller J, Schmidt A, Schmidt S, Schwachmeyer V, Schwanitz G, Seeger W, Stahl D, Stobäus N, Stubbe HC, Suttorp N, Temmesfeld B, Thun S, Triller P, Trinkmann F, Vadasz I, Valentin H, Vehreschild M, von Kalle C, von Lilienfeld-Toal M, Weber J, Welte T, Wildberg C, Wizimirski R, Zvork S, Sander LE, Vehreschild J, Zoller T, Kurth F, Witzenrath M

Infection 2024 Feb;52(1):93-104. doi: 10.1007/s15010-023-02057-0

MVA-based vaccine candidates encoding the native or prefusion-stabilized SARS-CoV-2 spike reveal differential immunogenicity in humans

Mayer L, Weskamm LM, Fathi A, Kono M, Heidepriem J, Krähling V, Mellinghoff SC, Ly ML, Friedrich M, Hardtke S, Borregaard S, Hesterkamp T, Loeffler FF, Volz A, Sutter G, Becker S, Dahlke C, Addo MM

NPJ Vaccines 2024 Jan 26;9(1):20. doi: 10.1038/s41541-023-00801-z

Detailed statistical analysis plan for ALBINO: effect of Allopurinol in addition to hypothermia for hypoxic-ischemic Brain Injury on Neurocognitive Outcome - a blinded randomized placebo-controlled parallel group multicenter trial for superiority (phase I

Engel C, Rüdiger M, Benders MJNL, van Bel F, Allegaert K, Naulaers G, Bassler D, Klebermaß-Schrehof K, Vento M, Vilan A, Falck M, Mauro I, Metsäranta M, Vanhatalo S, Mazela J, Metsvaht T, van der Vlught R, Franz AR; ALBINO Study Group

Trials 2024 Jan 24;25(1):81. doi: 10.1186/s13063-023-07828-6

Peptidyl nitroalkene inhibitors of main protease rationalized by computational and crystallographic investigations as antivirals against SARS-CoV-2

Medrano FJ, de la Hoz-Rodríguez S, Martí S, Arafet K, Schirmeister T, Hammerschmidt SJ, Müller C, González-Martínez Á, Santillana E, Ziebuhr J, Romero A, Zimmer C, Weldert A, Zimmermann R, Lodola A, Świderek K, Moliner V, González FV

Commun Chem 2024 Jan 18;7(1):15. doi: 10.1038/s42004-024-01104-7

Nucleated red blood cells are a late biomarker in predicting intensive care unit mortality in patients with COVID-19 acute respiratory distress syndrome: an observational cohort study

Schmidt G, Martens A, Koch C, Markmann M, Schneck E, Matt U, Hecker M, Tello K, Wolff M, Sander M, Vadász I

Front Immunol 2024 Jan 18;15:1313977. doi: 10.3389/fimmu.2024.1313977

Proteomic and transcriptomic characterisation of FIA10, a novel murine leukemic cell line that metastasizes into the brain

Just U, Burtscher H, Jeratsch S, Fischer M, Stocking C, Preussner J, Looso M, Schwanbeck R, Günther S, Huss R, Mullen L, Braun T

PLoS One 2024 Jan 12;19(1):e0295641. doi: 10.1371/journal.pone

Identification of a spike-specific CD8+ T cell epitope following vaccination against the Middle East respiratory syndrome coronavirus in humans

Harrer CE, Mayer L, Fathi A, Lassen S, Ly ML, Zinser ME, Wolf T, Becker S, Sutter G, Dahlke C, Addo MM; MVA-MERS-S Study Group

J Infect Dis 2024 Jan 9:jiad612. doi: 10.1093/infdis/jiad612

Hospitalisation patterns in interstitial lung diseases: data from the EXCITING-ILD registry

Buschulte K, Kabitz HJ, Hagmeyer L, Hammerl P, Esselmann A, Wiederhold C, Skowasch D, Stolpe C, Joest M, Veitshans S, Höffgen M, Maqhuzu P, Schwarzkopf L, Hellmann A, Pfeifer M, Behr J, Karpavicius R, Günther A, Polke M, Höger P, Somogyi V, Lederer C, Markart P, Kreuter M

Respir Res 2024 Jan 4;25(1):5. doi: 10.1186/s12931-023-02588-y

SIRT7 and p53 interaction in embryonic development and tumorigenesis

Vazquez BN, Fernández-Duran I, Hernandez Y, Tarighi S, Thackray JK, Espinosa-Alcantud M, Kumari P, Ianni A, Cesaire L, Braun T, Esteller M, Tischfield J, Vaquero A, Serrano L

Front Cell Dev Biol 2024 Jan 3;11:1281730. doi: 10.3389/fcell.2023.1281730

Alveolar macrophage-expressed Plet1 is a driver of lung epithelial repair after viral pneumonia

Pervizaj-Oruqaj L, Selvakumar B, Ferrero MR, Heiner M, Malainou C, Glaser RD, Wilhelm J, Bartkuhn M, Weiss A, Alexopoulos I, Witte B, Gattenlöhner S, Vadász I, Morty RE, Seeger W, Schermuly RT, Vazquez-Armendariz AI, Herold S

Nat Commun 2024 Jan 2;15(1):87. doi: 10.1038/s41467-023-44421-6

Distribution of ferritin complex in the adult brain and altered composition in neuroferritinopathy due to a novel variant in the ferritin heavy chain gene FTH1 (c.409_410del; p.H137Lfs*4)

Umathum V, Weber A, Amsel D, Alexopoulos I, Becker C, Roth A, Günther A, Selignow C, Ritschel N, Nishimura A, Schaiter A, Németh A, van der Ven PFM, Acker T, Schänzer A

Brain Pathol 2024 Jan;34(1):e13176. doi: 10.1111/bpa.13176