KFO309 - The clinical research unit Virus Induced Lung injury

All Publications

The Short- and Long-Range RNA-RNA Interactome of SARS-CoV-2

Ziv O, Price J, Shalamova L, Kamenova T, Goodfellow I, Weber F, Miska EA

Mol Cell 2020 Dec 17;80(6):1067-1077.e5. doi: 10.1016/j.molcel.2020.11.004

The H2S-generating enzyme 3-mercaptopyruvate sulfurtransferase regulates pulmonary vascular smooth muscle cell migration and proliferation but does not impact normal or aberrant lung development

Lignelli E, Palumbo F, Bayindir SG, Nagahara N, Vadász I, Herold S, Seeger W, Morty RE

Nitric Oxide 2021 Feb 1;107:31-45. doi: 10.1016/j.niox.2020.12.002

Longitudinal Multi-omics Analyses Identify Responses of Megakaryocytes, Erythroid Cells, and Plasmablasts as Hallmarks of Severe COVID-19

Bernardes JP, Mishra N, Tran F, Bahmer T, Best L, Blase JI, Bordoni D, Franzenburg J, Geisen U, Josephs-Spaulding J, Köhler P, Künstner A, Rosati E, Aschenbrenner AC, Bacher P, Baran N, Boysen T, Brandt B, Bruse N, Dörr J, Dräger A, Elke G, Ellinghaus D, Fischer J, Forster M, Franke A, Franzenburg S, Frey N, Friedrichs A, Fuß J, Glück A, Hamm J, Hinrichsen F, Hoeppner MP, Imm S, Junker R, Kaiser S, Kan YH, Knoll R, Lange C, Laue G, Lier C, Lindner M, Marinos G, Markewitz R, Nattermann J, Noth R, Pickkers P, Rabe KF, Renz A, Röcken C, Rupp J, Schaffarzyk A, Scheffold A, Schulte-Schrepping J, Schunk D, Skowasch D, Ulas T, Wandinger KP, Wittig M, Zimmermann J, Busch H, Hoyer BF, Kaleta C, Heyckendorf J, Kox M, Rybniker J, Schreiber S, Schultze JL, Rosenstiel P; HCA Lung Biological Network; Deutsche COVID-19 Omics Initiative (DeCOI)

Immunity 2020 Dec 15;53(6):1296-1314.e9. doi: 10.1016/j.immuni.2020.11.017

Bayesian Inference Associates Rare KDR Variants with Specific Phenotypes in Pulmonary Arterial Hypertension

Swietlik EM, Greene D, Zhu N, Megy K, Cogliano M, Rajaram S, Pandya D, Tilly T, Lutz KA, Welch CCL, Pauciulo MW, Southgate L, Martin JM, Treacy CM, Penkett CJ, Stephens JC, Bogaard HJ, Church C, Coghlan G, Coleman AW, Condliffe R, Eichstaedt CA, Eyries M, Gall H, Ghio S, Girerd B, Grünig E, Holden S, Howard L, Humbert M, Kiely DG, Kovacs G, Lordan J, Machado RD, Mackenzie Ross RV, McCabe C, Moledina S, Montani D, Olschewski H, Pepke-Zaba J, Price L, Rhodes CJ, Seeger W, Soubrier F, Suntharalingam J, Toshner MR, Vonk Noordegraaf A, Wharton J, Wild JM, Wort SJ, Lawrie A, Wilkins MR, Trembath RC, Shen Y, Chung WK, Swift AJ, Nichols WC, Morrell NW, Gräf S

Circ Genom Precis Med 2020 Dec 15;14(1):e003155. doi: 10.1161/CIRCGEN.120.003155

Physical Activity and Mental Health of Patients with Pulmonary Hypertension during the COVID-19 Pandemic

Dobler CL, Krüger B, Strahler J, Weyh C, Gebhardt K, Tello K, Ghofrani HA, Sommer N, Gall H, Richter MJ, Krüger K

J Clin Med 2020 Dec 12;9(12):4023. doi: 10.3390/jcm9124023

Lack of Contribution of p66shc to Pressure Overload-Induced Right Heart Hypertrophy

Hirschhäuser C, Sydykov A, Wolf A, Esfandiary A, Bornbaum J, Kutsche HS, Boengler K, Sommer N, Schreckenberg R, Schlüter KD, Weissmann N, Schermuly R, Schulz R

Int J Mol Sci 2020 Dec 8;21(24):9339. doi: 10.3390/ijms21249339

Non-basic amino acids in the hemagglutinin proteolytic cleavage site of a European H9N2 avian influenza virus modulate virulence in turkeys

Blaurock C, Scheibner D, Landmann M, Vallbracht M, Ulrich R, Böttcher-Friebertshäuser E, Mettenleiter TC, Abdelwhab EM

Sci Rep 2020 Dec 4;10(1):21226. doi: 10.1038/s41598-020-78210-8

Recombinant Rift Valley fever viruses encoding bluetongue virus (BTV) antigens: Immunity and efficacy studies upon a BTV-4 challenge

Moreno S, Calvo-Pinilla E, Devignot S, Weber F, Ortego J, Brun A

PLoS Negl Trop Dis 2020 Dec 4;14(12):e0008942. doi: 10.1371/journal.pntd.0008942

Differential effects of right and left heart failure on skeletal muscle in rats

Knapp F, Niemann B, Li L, Molenda N, Kracht M, Schulz R, Rohrbach S

J Cachexia Sarcopenia Muscle 2020 Dec;11(6):1830-1849. doi: 10.1002/jcsm.12612

A FOX-like Mechanism Regulating Lung Fibroblasts: Are We Getting There?

Pullamsetti SS, Günther A

Am J Respir Cell Mol Biol 2020 Dec;63(6):723-724. doi: 10.1165/rcmb.2020-0441ED

GnRH neurogenesis depends on embryonic pheromone receptor expression

Schmid T, Boehm U, Braun T

Mol Cell Endocrinol 2020 Dec 1;518:111030. doi: 10.1016/j.mce.2020.111030

Asthma-associated risk for COVID-19 development

Skevaki C, Karsonova A, Karaulov A, Xie M, Renz H

J Allergy Clin Immunol 2020 Dec;146(6):1295-1301. doi: 10.1016/j.jaci.2020.09.017

Genetic Deficiency and Pharmacological Stabilization of Mast Cells Ameliorate Pressure Overload-Induced Maladaptive Right Ventricular Remodeling in Mice

Sydykov A, Luitel H, Mamazhakypov A, Wygrecka M, Pradhan K, Pak O, Petrovic A, Kojonazarov B, Weissmann N, Seeger W, Grimminger F, Ghofrani HA, Kosanovic D, Schermuly RT

Int J Mol Sci 2020 Nov 30;21(23):9099. doi: 10.3390/ijms21239099

Profiling the Murine SUMO Proteome in Response to Cardiac Ischemia and Reperfusion Injury

Hotz PW, Wiesnet M, Tascher G, Braun T, Müller S, Mendler L

Molecules 2020 Nov 27;25(23):5571. doi: 10.3390/molecules25235571

Cyclophilin inhibitors restrict Middle East respiratory syndrome coronavirus via interferon-λ in vitro and in mice

Sauerhering L, Kupke A, Meier L, Dietzel E, Hoppe J, Gruber AD, Gattenloehner S, Witte B, Fink L, Hofmann N, Zimmermann T, Goesmann A, Nist A, Stiewe T, Becker S, Herold S, Peteranderl C

Eur Respir J 2020 Nov 26;56(5):1901826. doi: 10.1183/13993003.01826-2019