KFO309 - The clinical research unit Virus Induced Lung injury

All Publications

Clinical Relevance of Right Atrial Functional Response to Treatment in Pulmonary Arterial Hypertension

Richter MJ, Zedler D, Berliner D, Douschan P, Gall H, Ghofrani HA, Kimmig L, Kremer N, Olsson KM, Brita da Rocha B, Rosenkranz S, Seeger W, Yogeswaran A, Rako Z, Tello K

Front Cardiovasc Med 2021 Dec 7;8:775039. doi: 10.3389/fcvm.2021.775039

Unmasking right ventricular-arterial uncoupling during fluid challenge in pulmonary hypertension

Kremer N, Rako Z, Douschan P, Gall H, Ghofrani HA, Grimminger F, Guth S, Naeije R, Rieth A, Schulz R, Seeger W, Tedford RJ, Vadász I, Vanderpool R, Wiedenroth CB, Richter MJ, Tello K

J Heart Lung Transplant 2022 Mar;41(3):345-355. doi: 10.1016/j.healun.2021.11.019

Inhibition of SARS-CoV-2 coronavirus proliferation by designer antisense-circRNAs

Pfafenrot C, Schneider T, Müller C, Hung LH, Schreiner S, Ziebuhr J, Bindereif A

Nucleic Acids Res 2021 Dec 2;49(21):12502-12516. doi: 10.1093/nar/gkab1096

The role of glycosylation in the N-terminus of the hemagglutinin of a unique H4N2 with a natural polybasic cleavage site in virus fitness in vitro and in vivo

Gischke M, Bagato O, Breithaupt A, Scheibner D, Blaurock C, Vallbracht M, Karger A, Crossley B, Veits J, Böttcher-Friebertshäuser E, Mettenleiter TC, Abdelwhab EM

Virulence 2021 Dec;12(1):666-678. doi: 10.1080/21505594.2021

Hypercapnia Induces Inositol-Requiring Enzyme 1α-Driven Endoplasmic Reticulum-associated Degradation of the Na,K-ATPase β-Subunit

Kryvenko V, Wessendorf M, Tello K, Herold S, Morty RE, Seeger W, Vadász I

Am J Respir Cell Mol Biol 2021 Dec;65(6):615-629. doi: 10.1165/rcmb.2021-0114OC

Epidemiology and management of asthma and atopic dermatitis in Sub-Saharan Africa

Skevaki C, Ngocho JS, Amour C, Schmid-Grendelmeier P, Mmbaga BT, Renz H

J Allergy Clin Immunol 2021 Dec;148(6):1378-1386. doi: 10.1016/j.jaci.2021.10.019

The Collaborative Metadata Repository (CoMetaR) Web App: Quantitative and Qualitative Usability Evaluation

Stöhr MR, Günther A, Majeed RW

JMIR Med Inform 2021 Nov 29;9(11):e30308. doi: 10.2196/30308

SARS-CoV-2 infection triggers profibrotic macrophage responses and lung fibrosis

Wendisch D, Dietrich O, Mari T, von Stillfried S, Ibarra IL, Mittermaier M, Mache C, Chua RL; Knoll R, Timm S, Brumhard S, Krammer T, Zauber H, Hiller AL, Pascual-Reguant A, Mothes R, Bülow RD, Schulze J, Leipold AM, Djudjaj S, Erhard F, Geffers R, Pott F, Kazmierski J, Radke J, Pergantis P, Baßler K, Conrad C, Aschenbrenner AC, Sawitzki B, Landthaler M, Wyler E, Horst D, Deutsche COVID-19 OMICS Initiative (DECOI), Hippenstiel S, Hocke A, Heppner FL, Uhrig A, Garcia C, Machleidt F, Herold S, Elezkurtaj S, Thibeault C, Witzenrath M, Cochain C, Suttorp N, Drosten C, Goffinet C, Kurth F, Schultze JL, Radbruch H, Ochs M, Eils R, Müller-Redetzky H, Hauser AE, Luecken MD, Theis FJ, Conrad C, Wolff T, Boor P, Selbach M, Saliba A-E, Sander LE

Cell 2021 Dec 22; 184(26): 6243–6261.e27, doi: 10.1016/j.cell.2021.11.033

Sirt7 Deficiency Attenuates Neointimal Formation Following Vascular Injury by Modulating Vascular Smooth Muscle Cell Proliferation

Kimura Y, Izumiya Y, Araki S, Yamamura S, Hanatani S, Onoue Y, Ishida T, Arima Y, Nakamura T, Yamamoto E, Senokuchi T, Yoshizawa T, Sata M, Kim-Mitsuyama S, Nakagata N, Bober E, Braun T, Kaikita K, Yamagata K, Tsujita K

Circ J 2021 Nov 25;85(12):2232-2240. doi: 10.1253/circj.CJ-20-0936

Mechanisms of Hypercapnia-Induced Endoplasmic Reticulum Dysfunction

Kryvenko V, Vadász I

Front Physiol 2021 Nov 19;12:735580. doi: 10.3389/fphys.2021.735580. PMID: 34867444; PMCID: PMC8640499.

Renal markers for monitoring acute kidney injury transition to chronic kidney disease after COVID-19

Husain-Syed F, Villa G, Wilhelm J, Samoni S, Matt U, Vadász I, Tello K, Jennert B, Dietrich H, Trauth J, Kassoumeh S, Arneth B, Renz H, Sander M, Herold S, Seeger W, Schunk SJ, Speer T, Birk HW, Ronco C

Nephrol Dial Transplant 2021 Nov 9;36(11):2143-2147. doi: 10.1093/ndt/gfab235

Early IFN-α signatures and persistent dysfunction are distinguishing features of NK cells in severe COVID-19

Krämer B, Knoll R, Bonaguro L, ToVinh M, Raabe J, Astaburuaga-García R, Schulte-Schrepping J, Kaiser KM, Rieke GJ, Bischoff J, Monin MB, Hoffmeister C, Schlabe S, De Domenico E, Reusch N, Händler K, Reynolds G, Blüthgen N, Hack G, Finnemann C, Nischalke HD, Strassburg CP, Stephenson E, Su Y, Gardner L, Yuan D, Chen D, Goldman J, Rosenstiel P, Schmidt SV, Latz E, Hrusovsky K, Ball AJ, Johnson JM, Koenig PA, Schmidt FI, Haniffa M, Heath JR, Kümmerer BM, Keitel V, Jensen B, Stubbemann P, Kurth F, Sander LE, Sawitzki B; Deutsche COVID-19 OMICS Initiative (DeCOI); Aschenbrenner AC, Schultze JL, Nattermann J

Immunity 2021 Nov 9;54(11):2650-2669.e14. doi: 10.1016/j.immuni.2021.09.002

Flower lose, a cell fitness marker, predicts COVID-19 prognosis

Yekelchyk M, Madan E, Wilhelm J, Short KR, Palma AM, Liao L, Camacho D, Nkadori E, Winters MT, Rice ES, Rolim I, Cruz-Duarte R, Pelham CJ, Nagane M, Gupta K, Chaudhary S, Braun T, Pillappa R, Parker MS, Menter T, Matter M, Haslbauer JD, Tolnay M, Galior KD, Matkwoskyj KA, McGregor SM, Muller LK, Rakha EA, Lopez-Beltran A, Drapkin R, Ackermann M, Fisher PB, Grossman SR, Godwin AK, Kulasinghe A, Martinez I, Marsh CB, Tang B, Wicha MS, Won KJ, Tzankov A, Moreno E, Gogna R

EMBO Mol Med 2021 Nov 8;13(11):e13714. doi: 10.15252/emmm.202013714

Identification of a novel subset of alveolar type 2 cells enriched in PD-L1 and expanded following pneumonectomy

Ahmadvand N, Khosravi F, Lingampally A, Wasnick R, Vazquez-Armendariz AI, Carraro G, Heiner M, Rivetti S, Lv Y, Wilhelm J, Gunther A, Herold S, Al Alam D, Chen C, Minoo P, Zhang JS, Bellusci S

Eur Respir J 2021 Nov 4;58(5):2004168. doi: 10.1183/13993003.04168-2020

Evaluation of Diagnostic Accuracy and Radiation Exposure of Dual-Energy Computed Tomography (DECT) in the Course of Chronic Thromboembolic Pulmonary Hypertension (CTEPH)

Schüßler A, Richter M, Tello K, Steiner D, Seeger W, Krombach GA, Roller FC

Rofo 2021 Nov;193(11):1318-1326. English, German. doi: 10.1055/a-1502-7541