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Universitätsklinikum Marburg
Justus-Liebig-Universität Giessen
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KFO309 - The clinical research unit Virus Induced Lung injury

All Publications

New Challenges with Treatment Advances in Newborn Infants with Genetic Disorders and Severe Congenital Malformations

Schuler R, Bedei I, Oehmke F, Zimmer KP, Ehrhardt H

Children (Basel) 2022 Feb 10;9(2):236. doi: 10.3390/children9020236

ADAM8 signaling drives neutrophil migration and ARDS severity

Conrad C, Yildiz D, Cleary SJ, Margraf A, Cook L, Schlomann U, Panaretou B, Bowser JL, Karmouty-Quintana H, Li J, Berg NK, Martin SC, Aljohmani A, Moussavi-Harmami SF, Wang, KM, Tian JJ, Magnen M, Calet C, Qiu L, Sinder JP, Eltzschig HK, CAPSys Study Group, Bertrams W, Herold S, Suttorp N, Schmeck B, Ball ZT, Zarbock A, Looney MR, Bartsch JW

JCI Insight 2022 Feb 8; 7(3): e149870, doi: 10.1172/jci.insight.149870

Endogenous formaldehyde scavenges cellular glutathione resulting in redox disruption and cytotoxicity

Umansky C, Morellato AE, Rieckher M, Scheidegger MA, Martinefski MR, Fernández GA, Pak O, Kolesnikova K, Reingruber H, Bollini M, Crossan GP, Sommer N, Monge ME, Schumacher B, Pontel LB

Nat Commun 2022 Feb 8;13(1):745. doi: 10.1038/s41467-022-28242-7

Systemic Effects of mitoTEMPO upon Lipopolysaccharide Challenge Are Due to Its Antioxidant Part, While Local Effects in the Lung Are Due to Triphenylphosphonium

Weidinger A, Birgisdóttir L, Schäffer J, Meszaros AT, Zavadskis S, Müllebner A, Hecker M, Duvigneau JC, Sommer N, Kozlov AV

Antioxidants (Basel) 2022 Feb 6;11(2):323. doi: 10.3390/antiox11020323

Relayed signaling between mesenchymal progenitors and muscle stem cells ensures adaptive stem cell response to increased mechanical load

Kaneshige A, Kaji T, Zhang L, Saito H, Nakamura A, Kurosawa T, Ikemoto-Uezumi M, Tsujikawa K, Seno S, Hori M, Saito Y, Matozaki T, Maehara K, Ohkawa Y, Potente M, Watanabe S, Braun T, Uezumi A, Fukada SI

Cell Stem Cell 2022 Feb 3;29(2):265-280.e6. doi: 10.1016/j.stem.2021.11.003

Proteomic landscape of SARS-CoV-2- and MERS-CoV-infected primary human renal epithelial cells

Kohli A, Sauerhering L, Fehling SK, Klann K, Geiger H, Becker S, Koch B, Baer PC, Strecker T, Münch C

Life Sci Alliance 2022 Feb 2;5(5):e202201371. doi: 10.26508/lsa.202201371

Effects of BPA on right ventricular mechanical dysfunction in patients with inoperable CTEPH - A cardiac magnetic resonance study

Roller FC, Schüssler A, Hasse A, Kriechbaum S, Richter M, Guth S, Tello K, Breithecker A, Liebetrau C, Hamm CW, Mayer E, Seeger W, Krombach GA, Wiedenroth CB

Eur J Radiol 2022 Feb;147:110111. doi: 10.1016/j.ejrad.2021.110111

An essential function for autocrine hedgehog signaling in epithelial proliferation and differentiation in the trachea

Yin W, Liontos A, Koepke J, Ghoul M, Mazzocchi L, Liu X, Lu C, Wu H, Fysikopoulos A, Sountoulidis A, Seeger W, Ruppert C, Günther A, Stainier DYR, Samakovlis C

Development 2022 Feb 1;149(3):dev199804. doi: 10.1242/dev.199804

Sphingosine 1-phosphate receptor 1 governs endothelial barrier function and angiogenesis by upregulating endoglin signaling

Wang B, Dong N, Wu D, Fang Y, Chen J, Lin Y, Bellusci S, Zhang JS, Dai K, Chen C

Ann Transl Med 2022 Feb;10(3):136. doi: 10.21037/atm-21-6679

Update on the Features and Measurements of Experimental Acute Lung Injury in Animals: An Official American Thoracic Society Workshop Report

Kulkarni HS, Lee JS, Bastarache JA, Kuebler WM, Downey GP, Albaiceta GM, Altemeier WA, Artigas A, Bates JHT, Calfee CS, Dela Cruz CS, Dickson RP, Englert JA, Everitt JI, Fessler MB, Gelman AE, Gowdy KM, Groshong SD, Herold S, Homer RJ, Horowitz JC, Hsia CCW, Kurahashi K, Laubach VE, Looney MR, Lucas R, Mangalmurti NS, Manicone AM, Martin TR, Matalon S, Matthay MA, McAuley DF, McGrath-Morrow SA, Mizgerd JP, Montgomery SA, Moore BB, Noël A, Perlman CE, Reilly JP, Schmidt EP, Skerrett SJ, Suber TL, Summers C, Suratt BT, Takata M, Tuder R, Uhlig S, Witzenrath M, Zemans RL, Matute-Bello G

Am J Respir Cell Mol Biol 2022 Feb;66(2):e1-e14. doi: 10.1165/rcmb.2021-0531ST

Reduced decline of lung diffusing capacity in COPD patients with diabetes and metformin treatment

Kahnert K, Andreas S, Kellerer C, Lutter JI, Lucke T, Yildirim Ö, Lehmann M, Seissler J, Behr J, Frankenberger M, Bals R, Watz H, Welte T, Trudzinski FC, Vogelmeier CF, Alter P, Jörres RA; COSYCONET Study Group

Sci Rep 2022 Jan 26;12(1):1435. doi: 10.1038/s41598-022-05276-x

Picturing of the Lung Tumor Cellular Composition by Multispectral Flow Cytometry

Olesch C, Brunn D, Aktay-Cetin Ö, Sirait-Fischer E, Pullamsetti SS, Grimminger F, Seeger W, Brüne B, Weigert A, Savai R

Front Immunol 2022 Jan 25;13:827719. doi: 10.3389/fimmu.2022.827719

Based Therapies to Prevent or Treat BPD-A Narrative Review on Advances and Ongoing Challenges

Goetz MJ, Kremer S, Behnke J, Staude B, Shahzad T, Holzfurtner L, Chao CM, Morty RE, Bellusci S, Ehrhardt H

Int J Mol Sci 2021 Jan 24;22(3):1138. doi: 10.3390/ijms22031138

RNA-Cholesterol Nanoparticles Function as Potent Immune Activators via TLR7 and TLR8

Obermann HL, Lederbogen II, Steele J, Dorna J, Sander LE, Engelhardt K, Bakowsky U, Kaufmann A, Bauer S

Front Immunol 2022 Jan 21;12:658895. doi: 10.3389/fimmu.2021.658895

Autoantibodies targeting cytokines and connective tissue disease autoantigens are common in acute non-SARS-CoV-2 infections

Feng A, Yang E, Moore A, Dhingra S, Chang S, Yin X, Pi R, Mack E, Völkel S, Geßner R, Gundisch M, Neubauer A, Renz H, Tsiodras S, Fragkou P, Asuni A, Levitt J, Wilson J, Leong M, Lumb J, Mao R, Pinedo K, Roque J, Richards C, Stabile M, Swaminathan G, Salagianni M, Triantafyllia V, Bertrams W, Blish C, Carette J, Frankovich J, Meffre E, Nadeau KC, Singh U, Wang T, Luning Prak E, Herold S, Andreakos E, Schmeck B, Skevaki C, Rogers A, Utz P

Res Sq 2022 Jan 20;rs.3.rs-1233038. doi: 10.21203/rs.3.rs-1233038/v1. Preprint