KFO309 - The clinical research unit Virus Induced Lung injury

All Publications

Awareness and preparedness of healthcare workers against the first wave of the COVID-19 pandemic: A cross-sectional survey across 57 countries

Huy NT, Chico RM, Huan VT, Shaikhkhalil HW, Uyen VNT, Qarawi ATA, Alhady STM, Vuong NL, Truong LV, Luu MN, Dumre SP, Imoto A, Lee PN, Tam DNH, Ng SJ, Hashan MR, Matsui M, Duc NTM, Karimzadeh S, Koonrungsesomboon N, Smith C, Cox S, Moji K, Hirayama K, Linh LK, Abbas KS, Dung TNT, Mohammed Ali Al-Ahdal T, Balogun EO, Duy NT, Mohamed Eltaras M, Huynh T, Hue NTL, Khue BD, Gad A, Tawfik GM, Kubota K, Nguyen HM, Pavlenko D, Trang VTT, Vu LT, Hai Yen T, Yen-Xuan NT, Trang LT, Dong V, Sharma A, Dat VQ, Soliman M, Abdul Aziz J, Shah J, Hung PDL, Jee YS, Phuong DTH, Quynh TTH, Giang HTN, Huynh VTN, Thi NA, Dhouibi N, Phan T, Duru V, Nam NH, Ghozy S; contributors of the TMGH-Global COVID-19 Collaborative; TMGH-Global COVID-19 Collaborative

PLoS One 2021 Dec 22;16(12):e0258348. doi: 10.1371/journal.pone.0258348

Longitudinal Multi-omics Analyses Identify Responses of Megakaryocytes, Erythroid Cells, and Plasmablasts as Hallmarks of Severe COVID-19

Bernardes JP, Mishra N, Tran F, Bahmer T, Best L, Blase JI, Bordoni D, Franzenburg J, Geisen U, Josephs-Spaulding J, Köhler P, Künstner A, Rosati E, Aschenbrenner AC, Bacher P, Baran N, Boysen T, Brandt B, Bruse N, Dörr J, Dräger A, Elke G, Ellinghaus D, Fischer J, Forster M, Franke A, Franzenburg S, Frey N, Friedrichs A, Fuß J, Glück A, Hamm J, Hinrichsen F, Hoeppner MP, Imm S, Junker R, Kaiser S, Kan YH, Knoll R, Lange C, Laue G, Lier C, Lindner M, Marinos G, Markewitz R, Nattermann J, Noth R, Pickkers P, Rabe KF, Renz A, Röcken C, Rupp J, Schaffarzyk A, Scheffold A, Schulte-Schrepping J, Schunk D, Skowasch D, Ulas T, Wandinger KP, Wittig M, Zimmermann J, Busch H, Hoyer BF, Kaleta C, Heyckendorf J, Kox M, Rybniker J, Schreiber S, Schultze JL, Rosenstiel P; HCA Lung Biological Network; Deutsche COVID-19 Omics Initiative (DeCOI)

Immunity 2020 Dec 15;53(6):1296-1314.e9. doi: 10.1016/j.immuni.2020.11.017

Fibroblast growth factor 6 regulates sizing of the muscle stem cell pool

Zofkie W, Southard SM, Braun T, Lepper C

Stem Cell Reports 2021 Dec 14;16(12):2913-2927. doi: 10.1016/j.stemcr.2021.10.006

From mRNA sensing to vaccines

Fauci AS, Merad M, Swaminathan S, Hur S, Topol E, Fitzgerald K, Reis e Sousa C, Corbett KS, Bauer S

Immunity 2021 Dec 14;54(12):2676-2680. doi: 10.1016/j.immuni.2021.10.018

eIF2B-capturing viral protein NSs suppresses the integrated stress response

Kashiwagi K, Shichino Y, Osaki T, Sakamoto A, Nishimoto M, Takahashi M, Mito M, Weber F, Ikeuchi Y, Iwasaki S, Ito T

Nat Commun Dec 7;12(1):7102. doi: 10.1038/s41467-021-27337-x

Clinical Relevance of Right Atrial Functional Response to Treatment in Pulmonary Arterial Hypertension

Richter MJ, Zedler D, Berliner D, Douschan P, Gall H, Ghofrani HA, Kimmig L, Kremer N, Olsson KM, Brita da Rocha B, Rosenkranz S, Seeger W, Yogeswaran A, Rako Z, Tello K

Front Cardiovasc Med 2021 Dec 7;8:775039. doi: 10.3389/fcvm.2021.775039

Unmasking right ventricular-arterial uncoupling during fluid challenge in pulmonary hypertension

Kremer N, Rako Z, Douschan P, Gall H, Ghofrani HA, Grimminger F, Guth S, Naeije R, Rieth A, Schulz R, Seeger W, Tedford RJ, Vadász I, Vanderpool R, Wiedenroth CB, Richter MJ, Tello K

J Heart Lung Transplant 2022 Mar;41(3):345-355. doi: 10.1016/j.healun.2021.11.019

Inhibition of SARS-CoV-2 coronavirus proliferation by designer antisense-circRNAs

Pfafenrot C, Schneider T, Müller C, Hung LH, Schreiner S, Ziebuhr J, Bindereif A

Nucleic Acids Res 2021 Dec 2;49(21):12502-12516. doi: 10.1093/nar/gkab1096

Hypercapnia Induces Inositol-Requiring Enzyme 1α-Driven Endoplasmic Reticulum-associated Degradation of the Na,K-ATPase β-Subunit

Kryvenko V, Wessendorf M, Tello K, Herold S, Morty RE, Seeger W, Vadász I

Am J Respir Cell Mol Biol 2021 Dec;65(6):615-629. doi: 10.1165/rcmb.2021-0114OC

The role of glycosylation in the N-terminus of the hemagglutinin of a unique H4N2 with a natural polybasic cleavage site in virus fitness in vitro and in vivo

Gischke M, Bagato O, Breithaupt A, Scheibner D, Blaurock C, Vallbracht M, Karger A, Crossley B, Veits J, Böttcher-Friebertshäuser E, Mettenleiter TC, Abdelwhab EM

Virulence 2021 Dec;12(1):666-678. doi: 10.1080/21505594.2021

Epidemiology and management of asthma and atopic dermatitis in Sub-Saharan Africa

Skevaki C, Ngocho JS, Amour C, Schmid-Grendelmeier P, Mmbaga BT, Renz H

J Allergy Clin Immunol 2021 Dec;148(6):1378-1386. doi: 10.1016/j.jaci.2021.10.019

The Collaborative Metadata Repository (CoMetaR) Web App: Quantitative and Qualitative Usability Evaluation

Stöhr MR, Günther A, Majeed RW

JMIR Med Inform 2021 Nov 29;9(11):e30308. doi: 10.2196/30308

SARS-CoV-2 infection triggers profibrotic macrophage responses and lung fibrosis

Wendisch D, Dietrich O, Mari T, von Stillfried S, Ibarra IL, Mittermaier M, Mache C, Chua RL; Knoll R, Timm S, Brumhard S, Krammer T, Zauber H, Hiller AL, Pascual-Reguant A, Mothes R, Bülow RD, Schulze J, Leipold AM, Djudjaj S, Erhard F, Geffers R, Pott F, Kazmierski J, Radke J, Pergantis P, Baßler K, Conrad C, Aschenbrenner AC, Sawitzki B, Landthaler M, Wyler E, Horst D, Deutsche COVID-19 OMICS Initiative (DECOI), Hippenstiel S, Hocke A, Heppner FL, Uhrig A, Garcia C, Machleidt F, Herold S, Elezkurtaj S, Thibeault C, Witzenrath M, Cochain C, Suttorp N, Drosten C, Goffinet C, Kurth F, Schultze JL, Radbruch H, Ochs M, Eils R, Müller-Redetzky H, Hauser AE, Luecken MD, Theis FJ, Conrad C, Wolff T, Boor P, Selbach M, Saliba A-E, Sander LE

Cell 2021 Dec 22; 184(26): 6243–6261.e27, doi: 10.1016/j.cell.2021.11.033

Sirt7 Deficiency Attenuates Neointimal Formation Following Vascular Injury by Modulating Vascular Smooth Muscle Cell Proliferation

Kimura Y, Izumiya Y, Araki S, Yamamura S, Hanatani S, Onoue Y, Ishida T, Arima Y, Nakamura T, Yamamoto E, Senokuchi T, Yoshizawa T, Sata M, Kim-Mitsuyama S, Nakagata N, Bober E, Braun T, Kaikita K, Yamagata K, Tsujita K

Circ J 2021 Nov 25;85(12):2232-2240. doi: 10.1253/circj.CJ-20-0936

Mechanisms of Hypercapnia-Induced Endoplasmic Reticulum Dysfunction

Kryvenko V, Vadász I

Front Physiol 2021 Nov 19;12:735580. doi: 10.3389/fphys.2021.735580. PMID: 34867444; PMCID: PMC8640499.