KFO309 - The clinical research unit Virus Induced Lung injury

All Publications

Fibroblast growth factor 10 protects against particulate matter-induced lung injury by inhibiting oxidative stress-mediated pyroptosis via the PI3K/Akt/Nrf2 signaling pathway

Liu L, Shi Q, Wang K, Qian Y, Zhou L, Bellusci S, Chen C, Dong N

Int Immunopharmacol 2022 Dec;113(Pt A):109398. doi: 10.1016/j.intimp.2022.109398

Relationship between impaired BMP signalling and clinical risk factors at early-stage vascular injury in the preterm infant

Heydarian M, Oak P, Zhang X, Kamgari N, Kindt A, Koschlig M, Pritzke T, Gonzalez-Rodriguez E, Förster K, Morty RE, Häfner F, Hübener C, Flemmer AW, Yildirim AO, Sudheendra D, Tian X, Petrera A, Kirsten H, Ahnert P, Morrell N, Desai TJ, Sucre J, Spiekerkoetter E, Hilgendorff A

Thorax 2022 Dec;77(12):1176-1186. doi: 10.1136/thoraxjnl-2021-218083

GDF-15 and soluble ST2 as biomarkers of right ventricular dysfunction in pulmonary hypertension

Keranov S, Widmann L, Jafari L, Liebetrau C, Keller T, Troidl C, Kriechbaum S, Voss S, Bauer P, Richter MJ, Tello K, Gall H, Ghofrani HA, Wiedenroth CB, Guth S, Seeger W, Hamm CW, Nef H, Dörr O

Biomark Med 2022 Dec;16(17):1193-1207. doi: 10.2217/bmm-2022-0395

Circulating hyaluronic acid signature in CAP and ARDS - the role of pneumolysin in hyaluronic acid shedding

Sauer A, Seeliger B, Jandl K, Erfinanda L, Wilhelm J, Alexopoulos I, Baal N, Birnhuber A, David S, Welte T, Barreto G, Gaertner U, Kwapiszewska G, Seeger W, Kuebler WM, Schaefer L, Wygrecka M; members of the CAPNETZ Study Group

Matrix Biol 2022 Dec;114:67-83. doi: 10.1016/j.matbio.2022.11.003

Alternative oxidase encoded by sequence-optimized and chemically-modified RNA transfected into mammalian cells is catalytically active

Giordano L, Aneja MK, Sommer N, Alebrahimdehkordi N, Seraji A, Weissmann N, Rudolph C, Plank C, Jacobs HT, Szibor M

Gene Ther 2022 Dec;29(12):655-664. doi: 10.1038/s41434-021-00235-z

FGFR2b signalling restricts lineage-flexible alveolar progenitors during mouse lung development and converges in mature alveolar type 2 cells

Jones MR, Lingampally A, Ahmadvand N, Chong L, Wu J, Wilhem J, Vazquez-Armendariz AI, Ansari M, Herold S, Ornitz DM, Schiller HB, Chao CM, Zhang JS, Carraro G, Bellusci S

Cell Mol Life Sci 2022 Nov 29;79(12):609. doi: 10.1007/s00018-022-04626-2

ABO Incompatibility between the Mother and Fetus Does Not Protect against Anti-Human Platelet Antigen-1a Immunization by Pregnancy

Miserre L, Wienzek-Lischka S, Mann A, Cooper N, Santoso S, Ehrhardt H, Sachs UJ, Bein G

J Clin Med 2022 Nov 17;11(22):6811. doi: 10.3390/jcm11226811

Replication collisions induced by de-repressed S-phase transcription are connected with malignant transformation of adult stem cells

Zhang T, Künne C, Ding D, Günther S, Guo X, Zhou Y, Yuan X, Braun T

Nat Commun 2022 Nov 14;13(1):6907. doi: 10.1038/s41467-022-34577-y

Deep Transfer Learning Enables Robust Prediction of Antimicrobial Resistance for Novel Antibiotics

Ren Y, Chakraborty T, Doijad S, Falgenhauer L, Falgenhauer J, Goesmann A, Schwengers O, Heider D

Antibiotics (Basel) 2022 Nov 12;11(11):1611. doi: 10.3390/antibiotics11111611

Long-Term Pulmonary Dysfunction by Hyperoxia Exposure during Severe Viral Lower Respiratory Tract Infection in Mice

Lilien TA, Gunjak M, Myti D, Casado F, van Woensel JBM, Morty RE, Bem RA

Pathogens 2022 Nov 12;11(11):1334. doi: 10.3390/pathogens11111334

GLI1+ cells are a source of repair-supportive mesenchymal cells (RSMCs) during airway epithelial regeneration

Chu X, Lingampally A, Moiseenko A, Kheirollahi V, Vazquez-Armendariz AI, Koepke J, Khadim A, Kiliaris G, Shahriari Felordi M, Zabihi M, Shalashova I, Alexopoulos I, Günther S, Lebrigand K, Truchi M, Günther A, Braun T, Mari B, Samakovlis C, Li X, Seeger W, Herold S, Zhang JS, Bellusci S, El Agha E

Cell Mol Life Sci 2022 Nov 5;79(11):581. doi: 10.1007/s00018-022-04599-2

Phenotypic and genomic assessment of the potential threat of human spaceflight-relevant Staphylococcus capitis isolates under stress conditions

Siems K, Runzheimer K, Rehm A, Schwengers O, Heidler von Heilborn D, Kaser L, Arndt F, Neidhöfer C, Mengel JP, Parcina M, Lipski A, Hain T, Moeller R

Front Microbiol 2022 Nov 3;13:1007143. doi: 10.3389/fmicb.2022.1007143

IgA+ memory B-cells are significantly increased in patients with asthma and small airway dysfunction

Habener A, Grychtol R, Gaedcke S, DeLuca D, Dittrich AM, Happle C, Abdo M, Watz H, Pedersen F, König IR, Thiele D, Kopp MV, von Mutius E, Bahmer T, Rabe KF, Meyer-Bahlburg A, Hansen G; ALLIANCE Study Group as part of the German Center for Lung Research (DZL); Fuchs O, Roesler B, Welchering N, Kohistani-Greif N, Kurz J, Landgraf-Rauf K, Laubhahn K, Maison N, Liebl C, Schaub B, Ege M, Illi S, Hose A, Zeitlmann E, Berbig M, Marzi C, Schauberger C, Zissler U, Schmidt-Weber C, Ricklefs I, Diekmann G, Liboschik L, Voigt G, Sultansei L, Weckmann M, Nissen G, Kirsten AM, Waschki B, Herzmann C, Biller H, Gaede KI, Bovermann X, Steinmetz A, Husstedt BL, Nitsche C, Veith V, Szewczyk M, Brinkmann F, Malik A, Schwerk N, Dopfer C, Price M, Jirmo AC, Liu B, Calveron MR, Weber S, Foth S, Skevaki C, Renz H, Meyer M, Schildberg T, Rietschel E, van Koningsbruggen-Rietschel S, Alcazar M

Eur Respir J 2022 Nov 3;60(5):2102130. doi: 10.1183/13993003.02130-2021

HIF1α-AS1 is a DNA:DNA:RNA triplex-forming lncRNA interacting with the HUSH complex

Leisegang MS, Bains JK, Seredinski S, Oo JA, Krause NM, Kuo CC, Günther S, Sentürk Cetin N, Warwick T, Cao C, Boos F, Izquierdo Ponce J, Haydar S, Bednarz R, Valasarajan C, Fuhrmann DC, Preussner J, Looso M, Pullamsetti SS, Schulz MH, Jonker HRA, Richter C, Rezende F, Gilsbach R, Pflüger-Müller B, Wittig I, Grummt I, Ribarska T, Costa IG, Schwalbe H, Brandes RP

Nat Commun 2022 Nov 2;13(1):6563. doi: 10.1038/s41467-022-34252-2

Mitochondrial oxygen sensing of acute hypoxia in specialized cells - Is there a unifying mechanism?

Pak O, Nolte A, Knoepp F, Giordano L, Pecina P, Hüttemann M, Grossman LI, Weissmann N, Sommer N

Biochim Biophys Acta Bioenerg 2022 Nov 1;1863(8):148911. doi: 10.1016/j.bbabio.2022.148911