KFO309 - The clinical research unit Virus Induced Lung injury

All Publications

GWAS meta-analysis of intrahepatic cholestasis of pregnancy implicates multiple hepatic genes and regulatory elements

Dixon PH, Levine AP, Cebola I, Chan MMY, Amin AS, Aich A, Mozere M, Maude H, Mitchell AL, Zhang J; NIHR BioResource; Genomics England Research Consortium Collaborators; Chambers J, Syngelaki A, Donnelly J, Cooley S, Geary M, Nicolaides K, Thorsell M, Hague WM, Estiu MC, Marschall HU, Gale DP, Williamson C

Nat Commun 2022 Aug 17;13(1):4840. doi: 10.1038/s41467-022-29931-z

State of the Art in Idiopathic Pulmonary Fibrosis

El Agha E, Wygrecka M

Cells 2022 Aug 11;11(16):2487. doi: 10.3390/cells11162487

Improving the selectivity of 3-amidinophenylalanine-derived matriptase inhibitors

Pilgram O, Keils A, Benary GE, Müller J, Merkl S, Ngaha S, Huber S, Chevillard F, Harbig A, Magdolen V, Heine A, Böttcher-Friebertshäuser E, Steinmetzer T

Eur J Med Chem 2022 Aug 5;238:114437. doi: 10.1016/j.ejmech.2022.114437

FGF10 Therapeutic Administration Promotes Mobilization of Injury-Activated Alveolar Progenitors in a Mouse Fibrosis Model

Lv YQ, Cai GF, Zeng PP, Dhlamini Q, Chen LF, Chen JJ, Lyu HD, Mossahebi-Mohammadi M, Ahmadvand N, Bellusci S, Li X, Chen C, Zhang JS

Cells 2022 Aug 3;11(15):2396. doi: 10.3390/cells11152396

Correction: Sommer et al. Decreased Thymic Output Contributes to Immune Defects in Septic Patients. J. Clin. Med. 2020, 9, 2695

Sommer N, Noack S, Hecker A, Hackstein H, Bein G, Weissmann N, Seeger W, Mayer K, Hecker M

J Clin Med 2022 Aug 2;11(15):4497. doi: 10.3390/jcm11154497

Expression and activity of phosphodiesterase isoforms during epithelial mesenchymal transition: The role of phosphodiesterase 4

Kolosionek E, Savai R, Ghofrani HA, Weissmann N, Guenther A, Grimminger F, Seeger W, Banat GA, Schermuly RT, Pullamsetti SS

Mol Biol Cell 2022 Aug 1;33(9):cor2. doi: 10.1091/mbc.E09-01-0019_corr

[Pulmonary manifestations in long COVID]

Sommer N, Schmeck B

Inn Med (Heidelb) 2022 Aug;63(8):819-829. German. doi: 10.1007/s00108-022-01371-3

Combined fibre atrophy and decreased muscle regeneration capacity driven by mitochondrial DNA alterations underlie the development of sarcopenia

Kimoloi S, Sen A, Guenther S, Braun T, Brügmann T, Sasse P, Wiesner RJ, Pla-Martín D, Baris OR

J Cachexia Sarcopenia Muscle 2022 Aug;13(4):2132-2145. doi: 10.1002/jcsm.13026

Profiling the neurovascular unit unveils detrimental effects of osteopontin on the blood-brain barrier in acute ischemic stroke

Spitzer D, Guérit S, Puetz T, Khel MI, Armbrust M, Dunst M, Macas J, Zinke J, Devraj G, Jia X, Croll F, Sommer K, Filipski K, Freiman TM, Looso M, Günther S, Di Tacchio M, Plate KH, Reiss Y, Liebner S, Harter PN, Devraj K

Acta Neuropathol 2022 Aug;144(2):305-337. doi: 10.1007/s00401-022-02452-1

The German National Pandemic Cohort Network (NAPKON): rationale, study design and baseline characteristics

Schons M, Pilgram L, Reese JP, Stecher M, Anton G, Appel KS, Bahmer T, Bartschke A, Bellinghausen C, Bernemann I, Brechtel M, Brinkmann F, Brünn C, Dhillon C, Fiessler C, Geisler R, Hamelmann E, Hansch S, Hanses F, Hanß S, Herold S, Heyder R, Hofmann AL, Hopff SM, Horn A, Jakob C, Jiru-Hillmann S, Keil T, Khodamoradi Y, Kohls M, Kraus M, Krefting D, Kunze S, Kurth F, Lieb W, Lippert LJ, Lorbeer R, Lorenz-Depiereux B, Maetzler C, Miljukov O, Nauck M, Pape D, Püntmann V, Reinke L, Römmele C, Rudolph S, Sass J, Schäfer C, Schaller J, Schattschneider M, Scheer C, Scherer M, Schmidt S, Schmidt J, Seibel K, Stahl D, Steinbeis F, Störk S, Tauchert M, Tebbe JJ, Thibeault C, Toepfner N, Ungethüm K, Vadasz I, Valentin H, Wiedmann S, Zoller T, Nagel E, Krawczak M, von Kalle C, Illig T, Schreiber S, Witzenrath M, Heuschmann P, Vehreschild JJ; NAPKON Research Group

Eur J Epidemiol 2022 Aug;37(8):849-870. doi: 10.1007/s10654-022-00896-z

Assembly and transport of filovirus nucleocapsids

Dolnik O, Becker S

PLoS Pathog 2022 Jul 28;18(7):e1010616. doi: 10.1371/journal.ppat.1010616

Wnt5a Promotes AT1 and Represses AT2 Lineage-Specific Gene Expression in a Cell-Context-Dependent Manner

Li C, Peinado N, Smith SM, Zhou J, Gao F, Kohbodi G, Zhou B, Thornton ME, Grubbs BH, Lee MK, Bellusci S, Borok Z, Chen YW, Minoo P

Stem Cells 2022 Jul 27;40(7):691-703. doi: 10.1093/stmcls/sxac031

Maternal and perinatal obesity induce bronchial obstruction and pulmonary hypertension via IL-6-FoxO1-axis in later life

Selle J, Dinger K, Jentgen V, Zanetti D, Will J, Georgomanolis T, Vohlen C, Wilke R, Kojonazarov B, Klymenko O, Mohr J, V Koningsbruggen-Rietschel S, Rhodes CJ, Ulrich A, Hirani D, Nestler T, Odenthal M, Mahabir E, Nayakanti S, Dabral S, Wunderlich T, Priest J, Seeger W, Dötsch J, Pullamsetti SS, Alejandre Alcazar MA

Nat Commun 2022 Jul 27;13(1):4352. doi: 10.1038/s41467-022-31655-z

TMPRSS2, a novel host-directed drug target against SARS-CoV-2

Keller C, Böttcher-Friebertshäuser E, Lohoff M

Signal Transduct Target Ther 2022 Jul 23;7(1):251. doi: 10.1038/s41392-022-01084-x

L-lactate as an indicator for cellular metabolic status: An easy and cost-effective colorimetric L-lactate assay

Schmiedeknecht K, Kaufmann A, Bauer S, Venegas Solis F

PLoS One 2022 Jul 22;17(7):e0271818. doi: 10.1371/journal.pone.0271818