KFO309 - The clinical research unit Virus Induced Lung injury

All Publications

Spectrum of pathogen- and model-specific histopathologies in mouse models of acute pneumonia

Dietert K, Gutbier B, Wienhold SM, Reppe K, Jiang X, Yao L, Chaput C, Naujoks J, Brack M, Kupke A, Peteranderl C, Becker S, von Lachner C, Baal N, Slevogt H, Hocke AC, Witzenrath M, Opitz B, Herold S, Hackstein H, Sander LE, Suttorp N, Gruber AD

PLoS ONE 2017 12(11):e0188251

Restoration of Megalin-Mediated Clearance of Alveolar Protein as a Novel Therapeutic Approach for Acute Lung Injury

Vohwinkel CU, Buchäckert Y, Al-Tamari HM, Mazzocchi LC, Eltzschig HK, Mayer K, Morty RE, Herold S, Seeger W, Pullamsetti SS, Vadász I

ATSJournals 2017 57(5):589-602

TGF-β inhibits alveolar protein transport by promoting shedding, regulated intramembrane proteolysis, and transcriptional downregulation of megalin

Mazzocchi LCVohwinkel CUMayer K, Herold SMorty RESeeger WVadász I

AJPLung 2017 313 (5) L807-L824

A novel mouse Cre-driver line targeting Perilipin 2-expressing cells in the neonatal lung

Ntokou A, Szibor M, Rodriguez-Castillo JA, Quantius J, Herold S, El Agha E, Bellusci S, Salwig I, Braun T, Voswinckel R, Seeger W, Morty RE, Ahlbrecht K

Genesis 2017 55(12):e23080

Perturbations to lysyl oxidase expression broadly influence the transcriptome of lung fibroblasts

Mizikova I, Palumbo F, Tabi T, Herold S, Vadasz I, Mayer K, Seeger W, Morty RE

Physiol Genomics 2017 49(8):416-429. doi: 10.1152/physiolgenomics.00026.2017

Hypercapnia Impairs ENaC Cell Surface Stability by Promoting Phosphorylation, Polyubiquitination and Endocytosis of beta-ENaC in a Human Alveolar Epithelial Cell Line

Gwozdzinska P, Buchbinder BA, Mayer K, Herold S, Morty RE, Seeger W, Vadasz I

Front Immunol 2017 8:591 doi: 10.3389/fimmu.2017.00591

pH-optimum of hemagglutinin-mediated membrane fusion determines sensitivity of influenza A viruses to the interferon-induced antiviral state and IFITMs.

Gerlach T, Hensen L, Matrosovich T, Bergmann J, Winkler M, Peteranderl C, Klenk HD, Weber F, Herold S, Pöhlmann S, Matrosovich M.

J Virol. 2017 91(11) e00246-17 doi: 10.1128/JVI.00246-17

Influenza A Virus Virulence Depends on Two Amino Acids in the N-Terminal Domain of Its NS1 Protein To Facilitate Inhibition of the RNA-Dependent Protein Kinase PKR

Schierhorn KL, Jolmes F, Bespalowa J, Saenger S, Peteranderl C, Dzieciolowski J, Mielke M, Budt M, Pleschka S, Herrmann A, Herold S, Wolff T

J Virol 2017 91(10). pii: e00198-17. doi: 10.1128/JVI.00198-17

Inflammatory Responses Regulating Alveolar Ion Transport during Pulmonary Infections

Peteranderl C, Sznajder JI, Herold S, Lecuona E

Front Immunol 2017 8:446. doi: 10.3389/fimmu.2017.00446

Gas Exchange Disturbances Regulate Alveolar Fluid Clearance during Acute Lung Injury

Vadász I, Sznajder JI

Front Immunol 2017 8:757. doi: 10.3389/ mmu.2017.00757

Origin and Characterization of Alpha Smooth Muscle Actin-Positive Cells During Murine Lung Development

Moiseenko A, Kheirollahi V, Chao C-M,  Ahmadvand N, Quantius J, Wilhelm J,  Herold S,  Ahlbrecht T K, Morty RE, Rizvanov AA, Minoo P, El Agha E, Bellusci S

Stem Cells 2017 35(6):1566-1578 doi.org/10.1002/stem.2615

The NF-κB-dependent and -independent transcriptome and chromatin landscapes of human coronavirus 229E-infected cells

Poppe M, Wittig S, Jurida L, Bartkuhn M, Wilhelm J, Müller H, Beuerlein K, Karl N, Bhuju S, Ziebuhr J, Schmitz M L,  Kracht M

PLoS Pathog 2017 3(3): e1006286

The Impact of the Interferon/TNF-Related Apoptosis-Inducing Ligand Signaling Axis on Disease Progression in Respiratory Viral Infection and Beyond

Peteranderl C, Herold S

Front Immunol 2017 8:313. doi: 10.3389/fimmu.2017.00313

Stereological monitoring of mouse lung alveolarization from the early post-natal period to adulthood.

Pozarska A, Rodríguez-Castillo JA, Surate Solaligue DE, Ntokou A, Rath P, Mižíková I, Madurga A, Mayer K, Vadász I, Herold S, Ahlbrecht K, Seeger W, Morty RE.

Am J Physiol Lung Cell Mol Physiol 2017 312(6):L882-L895. doi: 10.1152/ajplung.00492.2016

Standardisation of oxygen exposure in the development of mouse models of bronchopulmonary dysplasia

Nardiello C, Mizikova I, Silva DM, Ruiz-Camp J, Mayer K, Vadasz I, Herold S, Seeger W, Morty RE

Dis Model Mech 2017 10(2): 185–196. doi: 10.1242/dmm.027086