Spectrum of pathogen- and model-specific histopathologies in mouse models of acute pneumonia
Dietert K, Gutbier B, Wienhold SM, Reppe K, Jiang X, Yao L, Chaput C, Naujoks J, Brack M, Kupke A, Peteranderl C, Becker S, von Lachner C, Baal N, Slevogt H, Hocke AC, Witzenrath M, Opitz B, Herold S, Hackstein H, Sander LE, Suttorp N, Gruber AD
PLoS ONE 2017 12(11):e0188251
Restoration of Megalin-Mediated Clearance of Alveolar Protein as a Novel Therapeutic Approach for Acute Lung Injury
Vohwinkel CU, Buchäckert Y, Al-Tamari HM, Mazzocchi LC, Eltzschig HK, Mayer K, Morty RE, Herold S, Seeger W, Pullamsetti SS, Vadász I
ATSJournals 2017 57(5):589-602
TGF-β inhibits alveolar protein transport by promoting shedding, regulated intramembrane proteolysis, and transcriptional downregulation of megalin
Mazzocchi LC, Vohwinkel CU, Mayer K, Herold S, Morty RE, Seeger W, Vadász I
AJPLung 2017 313 (5) L807-L824
A novel mouse Cre-driver line targeting Perilipin 2-expressing cells in the neonatal lung
Ntokou A, Szibor M, Rodriguez-Castillo JA, Quantius J, Herold S, El Agha E, Bellusci S, Salwig I, Braun T, Voswinckel R, Seeger W, Morty RE, Ahlbrecht K
Genesis 2017 55(12):e23080
Perturbations to lysyl oxidase expression broadly influence the transcriptome of lung fibroblasts
Mizikova I, Palumbo F, Tabi T, Herold S, Vadasz I, Mayer K, Seeger W, Morty RE
Physiol Genomics 2017 49(8):416-429. doi: 10.1152/physiolgenomics.00026.2017
Hypercapnia Impairs ENaC Cell Surface Stability by Promoting Phosphorylation, Polyubiquitination and Endocytosis of beta-ENaC in a Human Alveolar Epithelial Cell Line
Gwozdzinska P, Buchbinder BA, Mayer K, Herold S, Morty RE, Seeger W, Vadasz I
Front Immunol 2017 8:591 doi: 10.3389/fimmu.2017.00591
pH-optimum of hemagglutinin-mediated membrane fusion determines sensitivity of influenza A viruses to the interferon-induced antiviral state and IFITMs.
Gerlach T, Hensen L, Matrosovich T, Bergmann J, Winkler M, Peteranderl C, Klenk HD, Weber F, Herold S, Pöhlmann S, Matrosovich M.
J Virol. 2017 91(11) e00246-17 doi: 10.1128/JVI.00246-17
Influenza A Virus Virulence Depends on Two Amino Acids in the N-Terminal Domain of Its NS1 Protein To Facilitate Inhibition of the RNA-Dependent Protein Kinase PKR
Schierhorn KL, Jolmes F, Bespalowa J, Saenger S, Peteranderl C, Dzieciolowski J, Mielke M, Budt M, Pleschka S, Herrmann A, Herold S, Wolff T
J Virol 2017 91(10). pii: e00198-17. doi: 10.1128/JVI.00198-17
Inflammatory Responses Regulating Alveolar Ion Transport during Pulmonary Infections
Peteranderl C, Sznajder JI, Herold S, Lecuona E
Front Immunol 2017 8:446. doi: 10.3389/fimmu.2017.00446
Gas Exchange Disturbances Regulate Alveolar Fluid Clearance during Acute Lung Injury
Vadász I, Sznajder JI
Front Immunol 2017 8:757. doi: 10.3389/ mmu.2017.00757
Origin and Characterization of Alpha Smooth Muscle Actin-Positive Cells During Murine Lung Development
Moiseenko A, Kheirollahi V, Chao C-M, Ahmadvand N, Quantius J, Wilhelm J, Herold S, Ahlbrecht T K, Morty RE, Rizvanov AA, Minoo P, El Agha E, Bellusci S
Stem Cells 2017 35(6):1566-1578 doi.org/10.1002/stem.2615
The NF-κB-dependent and -independent transcriptome and chromatin landscapes of human coronavirus 229E-infected cells
Poppe M, Wittig S, Jurida L, Bartkuhn M, Wilhelm J, Müller H, Beuerlein K, Karl N, Bhuju S, Ziebuhr J, Schmitz M L, Kracht M
PLoS Pathog 2017 3(3): e1006286
The Impact of the Interferon/TNF-Related Apoptosis-Inducing Ligand Signaling Axis on Disease Progression in Respiratory Viral Infection and Beyond
Peteranderl C, Herold S
Front Immunol 2017 8:313. doi: 10.3389/fimmu.2017.00313
Stereological monitoring of mouse lung alveolarization from the early post-natal period to adulthood.
Pozarska A, Rodríguez-Castillo JA, Surate Solaligue DE, Ntokou A, Rath P, Mižíková I, Madurga A, Mayer K, Vadász I, Herold S, Ahlbrecht K, Seeger W, Morty RE.
Am J Physiol Lung Cell Mol Physiol 2017 312(6):L882-L895. doi: 10.1152/ajplung.00492.2016
Standardisation of oxygen exposure in the development of mouse models of bronchopulmonary dysplasia
Nardiello C, Mizikova I, Silva DM, Ruiz-Camp J, Mayer K, Vadasz I, Herold S, Seeger W, Morty RE
Dis Model Mech 2017 10(2): 185–196. doi: 10.1242/dmm.027086
