KFO309 - The clinical research unit Virus Induced Lung injury

All Publications

From Clones to Buds and Branches. The Use of Lung Organoids to Mod Branching Morphogenesis Ex Vivo

Vazquez-Armendariz, A.I. and Herold, S

Front Cell Dev Biol 9:631579 doi: 10.3389/fcell.2021.631579

Coronavirus replication–transcription complex: Vital and selective NMPylation of a conserved site in nsp9 by the NiRAN-RdRp subunit

Slanina H, Madhugiri RBylapudi GSchultheiß K, Karl N, Gulyaeva AGorbalenya AE,  Linne U, Ziebuhr J

PNAS 2021: 118 (6) e2022310118; https://doi.org/10.1073/pnas.2022310118

Coronavirus replication–transcription complex: Vital and selective NMPylation of a conserved site in nsp9 by the NiRAN-RdRp subunit

Slanina H, Madhugiri RBylapudi GSchultheiß K, Karl N, Gulyaeva AGorbalenya AE,  Linne U, Ziebuhr J

PNAS 2021: 118 (6) e2022310118; https://doi.org/10.1073/pnas.2022310118

The rocaglate CR-31-B (−) inhibits SARS-CoV-2 replication at non-cytotoxic, low nanomolar concentrations in vitro and ex vivo

Müller C, Obermann W, Karl N, Wendel, H-G, Taroncher-Oldenburg G, Pleschka S, Hartmann RK, Grünweller A, Ziebuhr J

Antiviral Res 186:195012, https://doi.org/10.1016/j.antiviral.2021.105012

A comparison of airway pressures for inflation fixation of developing mouse lungs for stereological analyses

Pérez-Bravo D, Myti D, Mižíková I, Pfeffer T, Surate Solaligue DE, Nardiello C, Vadász I, Herold S, Seeger W, Ahlbrecht K, Morty RE.

Histochem Cell Biol 2021 Feb;155(2):203-2014. doi 10.1007/s00418-020-01951-0

Identification of a Repair-Supportive Mesenchymal Cell Population during Airway Epithelial Regeneration

Moiseenko A, Vazquez-Armendariz AI, Kheirollahi V, Chu X, Tata A, Rivetti S, Günther S, Lebrigand K, Herold S, Braun T, Mari B, De Langhe S, Kwapiszewska G, Günther A, Chen C, Seeger W, Tata PR, Zhang JS, Bellusci S, El Agha E

Cell Rep 2020 Dec 22;33(12):108549. doi: 10.1016/j.celrep.2020.108549

The H2S-generating enzyme 3-mercaptopyruvate sulfurtransferase regulates pulmonary vascular smooth muscle cell migration and proliferation but does not impact normal or aberrant lung development

Lignelli E, Palumbo F, Bayindir SG, Nagahara N, Vadász I, Herold S, Seeger W, Morty RE

Nitric Oxide 2021 Feb 1;107:31-45. doi: 10.1016/j.niox.2020.12.002

Immunoglobulin Deficiency as an Indicator of Disease Severity in Patients with COVID-19

Husain-Syed F, Vadász I, Wilhelm J, Walmrath HD, Seeger W, Birk HW, Jennert B, Dietrich H, Herold S, Trauth J, Tello K, Sander M, Morty RE, Slanina H, Schüttler CG, Ziebuhr J, Kassoumeh S, Ronco C, Ferrari F, Warnatz K, Stahl K, Seeliger B, Hoeper MM, Welte T, David S

Am J Physiol Lung Cell Mol 2020 Nov 25. doi 10.1152/ajplung.00359.2020

Assessing the effectiveness of pirfenidone in idiopathic pulmonary fibrosis: Long-term, real-world data from european IPF registry (eurIPFreg)

Krauss E, Tello S, Wilhelm J, Schmidt J, Stoehr M, Seeger W, Dartsch RC, Crestani B, Guenther A

J Clin Med 2020 Nov 22;9(11):3763. doi: 10.3390/jcm9113763.

Extracorporeal Carbon Dioxide Removal Using a Renal Replacement Therapy Platform to Enhance Lung-Protective Ventilation in Hypercapnic Patients With Coronavirus Disease 2019-Associated Acute Respiratory Distress Syndrome

Husain-Syed F, Birk HW, Wilhelm J, Ronco C, Ranieri VM, Karle B, Kuhnert S, Tello K, Hecker M, Morty RE, Herold S, Kehl O, Walmrath HD, Seeger W, Vadász I

Front Med 2020 Nov 12;7:598379. doi: 10.3389/fmed.2020.598379

Severe organising pneumonia following COVID-19

Vadász I, Husain-Syed F, Dorfmüller P, Roller FC, Tello K, Hecker M, Morty RE, Gattenlöhner S, Walmrath HD, Grimminger F, Herold S, Seeger W

Thorax 2020 Nov 11;thorayjnl-2020-216088. doi: 10.1136/thoraxjnl-2020-216088

A ribosomal RNA fragment with 2',3'-cyclic phosphate and GTP-binding activity acts as RIG-I ligand

Jung S, von Thülen T, Yang I, Laukemper V, Rupf B, Janga H, Panagiotidis GD, Schoen A, Nicolai M, Schulte LN, Obermann HL, Weber F, Kaufmann A, Bauer S.

Nucleic Acid Res 2020 Oct 9;48(18):10397-10412. doi: 10.1093/nar/gkaa739

Minoxidil Cannot Be Used To Target Lysyl Hydroxylases during Postnatal Mouse Lung Development: A Cautionary Note

Pfeffer T, Lignelli E, Inoue H, Mižíková I, Surate Solaligue DE, Steenbock H, Myti D, Vadász I, Herold S, Seeger W, Brinckmann J, Morty RE

J Pharmacol Exp Ther 2020 Dec; 375(3):478-487. doi: 10.1124/jpet.120.000138

Multilineage murine stem cells generate complex organoids to model distal lung development and disease

Vazquez‐Armendariz AI, Heiner M, El Agha E, Salwig I, Hoek A, Hessler MC, Shalashova I, Amit Shrestha A, Carraro G, Mengel JP, Günther A, Morty RE, Vadász I, Schwemmle M, Kummer W, Hain T, Goesmann A, Bellusci S, Seeger W, Braun T, Herold S,

EMBO J 2020 39:e103476 doi.org/10.15252/embj.2019103476

Elevated FiO2 increases SARS-CoV-2 co-receptor expression in respiratory tract epithelium

Myti D, Gunjak M, Casado F, Khaghani Raziabad S, Nardiello C, Vadász I, Herold S, Pryhuber G, Seeger W, Morty RE

Am J Physiol Lung Cell Mol Physiol 2020 Oct 1;319(4):L670-L674. doi: 10.1152/ajplung.00345.2020