KFO309 - The clinical research unit Virus Induced Lung injury

All Publications

FGF10 triggers de novo alveologenesis in a BPD model: impact on the resident mesenchymal niche cells

Taghizadeh S, Chao C-M, Guenther S, Glaser L, Gersmann L, Michel G, Kraut S, Goth K, Koepke J, Heiner M, Vazquez-Armendariz AI, Herold S, Samakovlis C, Weissmann N, Ricci F, Aquila G, Boyer L, Erhardt H, Minoo P, Bellusci S, Rivetti S

Stem Cells 2022 Apr 19 sxac025. doi: 10.1093/stmcls/sxac025

Fgfr2b signaling is essential for the maintenance of the alveolar epithelial type 2 lineage during lung homeostasis in mice

Ahmadvand N, Lingampally A, Khosravi F, Vazquez-Armendariz I, Rivetti S, Jones MR, Wilhelm J, Herold S, Barreto G, Koepke J, Samakovlis C, Carraro G, Zhang J-S, Al Alam D, Bellusci S

Cell Mol Life Sci 2022 19;79(6):302. doi: 10.1007/s00018-022-04327-w

Thapsigargin: key to new host-directed coronavirus antivirals?

Shaban MS, Mayr-Buro C, Meier-Soelch, Albert BV, Schmitz ML, Ziebuhr J, Kracht M

TIPS 2022 doi.10.1016/j.tips.2022.04.004

Cyclosporin A Reveals Potent Antiviral Effects in Preclinical Models of SARS-CoV-2 Infection

Sauerhering L, Kuznetsova I, Kupke A, Meier L, Halwe S, Rohde C, Schmidt J, Morty RE, Danov O, Braun A, Vadász I, Becker B, Herold S

Am J Respir Crit Care 2022 Apr 15;205(8):964-968. doi: 10.1164/rccm.202108-1830LE

3D In Vitro Models: Novel Insights into Idiopathic Pulmonary Fibrosis Pathophysiology and Drug Screening

Vazquez-Armendariz AI, Barroso MM, El Agha E, Herold, S

Cells 11 (9):1526 doi.org/10.3390/cells11091526

ADAM8 signaling drives neutrophil migration and ARDS severity

Conrad C, Yildiz D, Cleary SJ, Margraf A, Cook L, Schlomann U, Panaretou B, Bowser JL, Karmouty-Quintana H, Li J, Berg NK, Martin SC, Aljohmani A, Moussavi-Harmami SF, Wang, KM, Tian JJ, Magnen M, Calet C, Qiu L, Sinder JP, Eltzschig HK, CAPSys Study Group, Bertrams W, Herold S, Suttorp N, Schmeck B, Ball ZT, Zarbock A, Looney MR, Bartsch JW

JCI Insight 2022 Feb 8; 7(3): e149870, doi: 10.1172/jci.insight.149870

Autoantibodies targeting cytokines and connective tissue disease autoantigens are common in acute non-SARS-CoV-2 infections

Feng A, Yang E, Moore A, Dhingra S, Chang S, Yin X, Pi R, Mack E, Völkel S, Geßner R, Gundisch M, Neubauer A, Renz H, Tsiodras S, Fragkou P, Asuni A, Levitt J, Wilson J, Leong M, Lumb J, Mao R, Pinedo K, Roque J, Richards C, Stabile M, Swaminathan G, Salagianni M, Triantafyllia V, Bertrams W, Blish C, Carette J, Frankovich J, Meffre E, Nadeau KC, Singh U, Wang T, Luning Prak E, Herold S, Andreakos E, Schmeck B, Skevaki C, Rogers A, Utz P

Res Sq 2022 Jan 20;rs.3.rs-1233038. doi: 10.21203/rs.3.rs-1233038/v1. Preprint

SARS-CoV-2 infection triggers profibrotic macrophage responses and lung fibrosis

Wendisch D, Dietrich O, Mari T, von Stillfried S, Ibarra IL, Mittermaier M, Mache C, Chua RL; Knoll R, Timm S, Brumhard S, Krammer T, Zauber H, Hiller AL, Pascual-Reguant A, Mothes R, Bülow RD, Schulze J, Leipold AM, Djudjaj S, Erhard F, Geffers R, Pott F, Kazmierski J, Radke J, Pergantis P, Baßler K, Conrad C, Aschenbrenner AC, Sawitzki B, Landthaler M, Wyler E, Horst D, Deutsche COVID-19 OMICS Initiative (DECOI), Hippenstiel S, Hocke A, Heppner FL, Uhrig A, Garcia C, Machleidt F, Herold S, Elezkurtaj S, Thibeault C, Witzenrath M, Cochain C, Suttorp N, Drosten C, Goffinet C, Kurth F, Schultze JL, Radbruch H, Ochs M, Eils R, Müller-Redetzky H, Hauser AE, Luecken MD, Theis FJ, Conrad C, Wolff T, Boor P, Selbach M, Saliba A-E, Sander LE

Cell 2021 Dec 22; 184(26): 6243–6261.e27, doi: 10.1016/j.cell.2021.11.033

Multi-level inhibition of coronavirus replication by chemical ER stress

Samer-Shaban M, Müller C, Mayr-Buro C, Weiser H, Meier-Soelch J, Albert BV, Weber A, Linne U, Hain T, Babayev I, Karl N, Hofmann N, Becker S, Herold S, Schmitz ML, Ziebuhr J, Kracht M

Nat Commun 2021; 12: 5536, doi: 10.1038/s41467-021-25551-1

TRAF2 Is a Novel Ubiquitin E3 Ligase for the Na,K-ATPase β-Subunit That Drives Alveolar Epithelial Dysfunction in Hypercapnia

Gabrielli NM, Mazzocchi LC, Kryvenko V, Tello K, Herold S, Morty RE, Grimminger F, Dada LA, Seeger W, Sznaijder JL, Vadász I

Front Cell Dev Biol 2021 Jul 2;9:689983. doi: 10.3389/fcell.2021.689983

Hypercapnia Induces Inositol-Requiring Enzyme 1α–Driven Endoplasmic Reticulum–associated Degradation of the Na,K-ATPase β-Subunit

Kryvenko V, Wessendorf M, Tello K, Herold S, Morty RE, Seeger W, Vadász I

Am J Respir Cell Mol Biol 2021 Dec;65(6):615-629. doi: 10.1165/rcmb.2021-0114OC

Protocol for the generation of murine bronchiolospheres

Vazquez-Armendariz AI, Seeger W, Herold S, El Agha E

STAR Protoc 2021 Jun 11;2(2):100594. doi: 10.1016/j.xpro.2021.100594

Characterization in Mice of the Resident Mesenchymal Niche Maintaining At2 Stem Cell Proliferation in Homeostasis and Disease

Taghizadeh S, Heiner M, Vazquez-Armendariz AI, Wilhelm J, Herold S, Chen C, Zhang JS, Bellusci S

Stem Cells 2021 Oct;39(10):1382-1394. doi: 10.1002/stem.3423

WASP: a versatile, web-accessible single cell RNA-Seq processing platform

Hoek A, Maibach K, Özmen E, Vasquez-Armendariz AI, Mengel JP, Hain T, Herold S, Goesmann A

BMC Genomics 2021 Mar 18;22(1):195. doi: 10.1186/s12864-021-07469-6

Validation of a Novel Fgf10Cre–ERT2 Knock-in Mouse Line Targeting FGF10Pos Cells Postnatally

Chu, X, Taghizadeh S, Vazquez-Armendariz AI, Herold S, Chong L, Chen C, Zhang, J-S, El Agha E, Bellusci S

Front Cell Dev Biol 2021 May 13;9:671841. doi: 10.3389/fcell.2021.671841