KFO309 - The clinical research unit Virus Induced Lung injury

All Publications

The rocaglate CR-31-B (−) inhibits SARS-CoV-2 replication at non-cytotoxic, low nanomolar concentrations in vitro and ex vivo

Müller C, Obermann W, Karl N, Wendel, H-G, Taroncher-Oldenburg G, Pleschka S, Hartmann RK, Grünweller A, Ziebuhr J

Antiviral Res 186:195012, https://doi.org/10.1016/j.antiviral.2021.105012

Platon: identification and characterization of bacterial plasmid contigs in short-read draft assemblies exploiting protein sequence-based replicon distribution scores

Schengers O, Barth P, Falgenhauer L, Hain T, Chakraborty T, Goesmann A

Microbial Genomics 2020 doi 10.1099/mgen.0.000398

Laboratory characteristics of patients infected with the novel SARS-CoV-2 virus

Skevaki C, Fragkou PC, Cheng C, Xie M, Renz H

J Infect 2020 doi.org/10.1016/j.jinf.2020.06.039

Using Experimental Models to Identify Pathogenic Pathways and Putative Disease Management Targets in Bronchopulmonary Dysplasia

Morty R

Neonatology doi:10.1159/000506989

Current and Future Point-of-Care Tests for Emerging and New Respiratory Viruses and Future Perspectives

Nelson P, Rath BA, Fragkou P, Antalis E, Tsiodras S, Skevaki C on behalf of the ESCMID Study Group for Respiratory Viruses (ESGREV)

Front Cell Infect Microbiol 2020 10:181

SARS-CoV-2 entry factors are highly expressed in nasal epithelial cells together with innate immune genes

Sungnak W, Huang N, Bécavin C, Berg M, Queen R, Litvinukova M, Talavera-López C, Maatz H, Reichart D, Sampaziotis F, Worlock KB, Yoshida M, Barnes JL & HCA Lung Biological Network

Nature Medicine 2020 26,681-687

Evidence for Overlapping and Distinct Biological Activities and Transcriptional Targets Triggered by Fibroblast Growth Factor Receptor 2b Signaling between Mid- and Early Pseudoglandular Stages of Mouse Lung Development

Jones M, Lingampally A, Wu J, Sedighi J, Ahmadvand N, Wilhelm J, Vazquez-Armendariz I, Herold S, Chen C, Zhang JS, Bellusci S, Chao CM

Cells 2020 9:1274

Failure to Down-Regulate miR-154 Expression in Early Postnatal Mouse Lung Epithelium Suppresses Alveologenesis, with Changes in Tgf-β Signaling Similar to those Induced by Exposure to Hyperoxia

Chao CM, Carraro G, Rako ZA, Kolck J, Sedighi J, Zimmermann V, Moiseenko A, Wilhelm J, Young BM, Chong L, Wu J, Contreras A, Minoo P, Barreto G, Warburton D, Bellusci S

Cells 2020 Apr 2;9(4). pii: E859. doi: 10.3390/cells9040859

Virus-Induced T Cell-Mediated Heterologous Immunity and Vaccine Development

Balz K, Trassl L, Härtel V, Nelson PP, Skevaki C

Front Immunol 11:513. doi: 10.3389/fimmu.2020.00513

Comparison of broad-spectrum antiviral activities of the synthetic rocaglate CR-31-B (−) and the eIF4A-inhibitor Silvestrol

Müller C, Obermann W, Schulte FW, Lange-Grünweller K, Oesterreich L, Elgner F, Glitscher M, Hildt E, Singh K, Wendel H-G, Hartmann RK, Ziebuhr J, Grünweller A

Antiviral Res 2020 175:104706, doi.org/10.1016/j.antiviral.2020.104706

Toward a universal flu vaccine

Herold S, Sander LE

Science 2020 376(6480): 852-53 doi: 10.1126/science.aba2754

Hypercapnia Impairs Na,K-ATPase Function by Inducing Endoplasmic Reticulum Retention of the β-Subunit of the Enzyme in Alveolar Epithelial Cells

Kryvenko V, Wessendorf M, Morty RE, Herold S, Seeger W, Vagin O, Dada LA, Sznajder JI, Vadász I

Int J Mol Sci 2020 21:2167

Good Things Come in 2's: Type 2 Alveolar Epithelial Cells and Fibroblast Growth Factor Receptor 2

Shimbori C, El Agha E

AJRCMB 2020 doi.org/10.1165/rcmb.2020-0013ED

Role of FGF10/FGFR2b Signaling in Mouse Digestive Tract Development, Repair and Regeneration Following Injury

Lv Y-Q, Wu J, Li X-K, Zhang J-S, Bellusci S

Front Cell Dev Biol 2019 7:326.doi: 10.3389/fcell.2019.00326

Recent advances in our understanding of the mechanisms of lung alveolarization and bronchopulmonary dysplasia

Lignelli E, Palumbo F, Myto D, Morty RE

Am J Physiol Lung Cell Mol Physiol2019 Dec 1;317(6):L832-L887