Coronavirus replication–transcription complex: Vital and selective NMPylation of a conserved site in nsp9 by the NiRAN-RdRp subunit
Slanina H, Madhugiri R, Bylapudi G, Schultheiß K, Karl N, Gulyaeva A, Gorbalenya AE, Linne U, Ziebuhr J
PNAS 2021: 118 (6) e2022310118; https://doi.org/10.1073/pnas.2022310118
Coronavirus replication–transcription complex: Vital and selective NMPylation of a conserved site in nsp9 by the NiRAN-RdRp subunit
Slanina H, Madhugiri R, Bylapudi G, Schultheiß K, Karl N, Gulyaeva A, Gorbalenya AE, Linne U, Ziebuhr J
PNAS 2021: 118 (6) e2022310118; https://doi.org/10.1073/pnas.2022310118
The rocaglate CR-31-B (−) inhibits SARS-CoV-2 replication at non-cytotoxic, low nanomolar concentrations in vitro and ex vivo
Müller C, Obermann W, Karl N, Wendel, H-G, Taroncher-Oldenburg G, Pleschka S, Hartmann RK, Grünweller A, Ziebuhr J
Antiviral Res 186:195012, https://doi.org/10.1016/j.antiviral.2021.105012
A comparison of airway pressures for inflation fixation of developing mouse lungs for stereological analyses
Pérez-Bravo D, Myti D, Mižíková I, Pfeffer T, Surate Solaligue DE, Nardiello C, Vadász I, Herold S, Seeger W, Ahlbrecht K, Morty RE.
Histochem Cell Biol 2021 Feb;155(2):203-2014. doi 10.1007/s00418-020-01951-0
Identification of a Repair-Supportive Mesenchymal Cell Population during Airway Epithelial Regeneration
Moiseenko A, Vazquez-Armendariz AI, Kheirollahi V, Chu X, Tata A, Rivetti S, Günther S, Lebrigand K, Herold S, Braun T, Mari B, De Langhe S, Kwapiszewska G, Günther A, Chen C, Seeger W, Tata PR, Zhang JS, Bellusci S, El Agha E
Cell Rep 2020 Dec 22;33(12):108549. doi: 10.1016/j.celrep.2020.108549
The H2S-generating enzyme 3-mercaptopyruvate sulfurtransferase regulates pulmonary vascular smooth muscle cell migration and proliferation but does not impact normal or aberrant lung development
Lignelli E, Palumbo F, Bayindir SG, Nagahara N, Vadász I, Herold S, Seeger W, Morty RE
Nitric Oxide 2021 Feb 1;107:31-45. doi: 10.1016/j.niox.2020.12.002
Immunoglobulin Deficiency as an Indicator of Disease Severity in Patients with COVID-19
Husain-Syed F, Vadász I, Wilhelm J, Walmrath HD, Seeger W, Birk HW, Jennert B, Dietrich H, Herold S, Trauth J, Tello K, Sander M, Morty RE, Slanina H, Schüttler CG, Ziebuhr J, Kassoumeh S, Ronco C, Ferrari F, Warnatz K, Stahl K, Seeliger B, Hoeper MM, Welte T, David S
Am J Physiol Lung Cell Mol 2020 Nov 25. doi 10.1152/ajplung.00359.2020
Assessing the effectiveness of pirfenidone in idiopathic pulmonary fibrosis: Long-term, real-world data from european IPF registry (eurIPFreg)
Krauss E, Tello S, Wilhelm J, Schmidt J, Stoehr M, Seeger W, Dartsch RC, Crestani B, Guenther A
J Clin Med 2020 Nov 22;9(11):3763. doi: 10.3390/jcm9113763.
Extracorporeal Carbon Dioxide Removal Using a Renal Replacement Therapy Platform to Enhance Lung-Protective Ventilation in Hypercapnic Patients With Coronavirus Disease 2019-Associated Acute Respiratory Distress Syndrome
Husain-Syed F, Birk HW, Wilhelm J, Ronco C, Ranieri VM, Karle B, Kuhnert S, Tello K, Hecker M, Morty RE, Herold S, Kehl O, Walmrath HD, Seeger W, Vadász I
Front Med 2020 Nov 12;7:598379. doi: 10.3389/fmed.2020.598379
Severe organising pneumonia following COVID-19
Vadász I, Husain-Syed F, Dorfmüller P, Roller FC, Tello K, Hecker M, Morty RE, Gattenlöhner S, Walmrath HD, Grimminger F, Herold S, Seeger W
Thorax 2020 Nov 11;thorayjnl-2020-216088. doi: 10.1136/thoraxjnl-2020-216088
A ribosomal RNA fragment with 2',3'-cyclic phosphate and GTP-binding activity acts as RIG-I ligand
Jung S, von Thülen T, Yang I, Laukemper V, Rupf B, Janga H, Panagiotidis GD, Schoen A, Nicolai M, Schulte LN, Obermann HL, Weber F, Kaufmann A, Bauer S.
Nucleic Acid Res 2020 Oct 9;48(18):10397-10412. doi: 10.1093/nar/gkaa739
Minoxidil Cannot Be Used To Target Lysyl Hydroxylases during Postnatal Mouse Lung Development: A Cautionary Note
Pfeffer T, Lignelli E, Inoue H, Mižíková I, Surate Solaligue DE, Steenbock H, Myti D, Vadász I, Herold S, Seeger W, Brinckmann J, Morty RE
J Pharmacol Exp Ther 2020 Dec; 375(3):478-487. doi: 10.1124/jpet.120.000138
Multilineage murine stem cells generate complex organoids to model distal lung development and disease
Vazquez‐Armendariz AI, Heiner M, El Agha E, Salwig I, Hoek A, Hessler MC, Shalashova I, Amit Shrestha A, Carraro G, Mengel JP, Günther A, Morty RE, Vadász I, Schwemmle M, Kummer W, Hain T, Goesmann A, Bellusci S, Seeger W, Braun T, Herold S,
EMBO J 2020 39:e103476 doi.org/10.15252/embj.2019103476
Elevated FiO2 increases SARS-CoV-2 co-receptor expression in respiratory tract epithelium
Myti D, Gunjak M, Casado F, Khaghani Raziabad S, Nardiello C, Vadász I, Herold S, Pryhuber G, Seeger W, Morty RE
Am J Physiol Lung Cell Mol Physiol 2020 Oct 1;319(4):L670-L674. doi: 10.1152/ajplung.00345.2020
ATAC-seq footprinting unravels kinetics of transcription factor binding during zygotic genome activation
Bentsen M, Goymann P, Schultheis H, Klee K, Petrova A, Wiegandt R, Fust A, Preussner J, Kuenne C, Braun T, Kim J, Looso M
Nat Commun 2020 Aug 26;11(1):4267. doi: 10.1038/s41467-020-18035-1
